This chapter reviews measures of emergence, self-organization, complexity, homeostasis, and autopoiesis based on information theory. These measures are derived from proposed axioms and tested in two case studies: random Boolean networks and an Arctic lake ecosystem.Emergence is defined as the information a system or process produces. Self-organization is defined as the opposite of emergence, while complexity is defined as the balance between emergence and self-organization. Homeostasis reflects the stability of a system. Autopoiesis is defined as the ratio between the complexity of a system and the complexity of its environment. The proposed measures can be applied at different scales, which can be studied with multi-scale profiles.