Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society

Kuwano, Hiroyuki; Nishimura, Yasumasa; Oyama, Tsuneo; Kato, Hiroyuki; Kitagawa, Yuko; Kusano, Motoyasu; Sasaki, Hideo; Takiuchi, Hiroya; Toh, Yasushi; Doki, Yuichiro; Naomoto, Yoshio; Matsubara, Hisahiro; Miyazaki, Tatsuya; Muto, Manabu; Yanagisawa, Akio

doi:10.1007/s10388-014-0465-1

Cited by 404 publications

(217 citation statements)

References 0 publications

Supporting

Mentioning

208

Contrasting

Unclassified

Order By: Relevance

“…The role of adjuvant therapy for squamous cell carcinoma of the esophagus for patients who receive three‐field lymph node dissection has been explored in several multi‐institutional randomized control trials in Japan. Survival benefit with adjuvant chemotherapy for esophageal cancer was first demonstrated, and a subsequent trial went on to show that neoadjuvant chemotherapy was superior to adjuvant chemotherapy in terms of overall survival, and the former has now become the standard treatment in Japan 11. The role of radiotherapy in addition to chemotherapy in the context of three‐field lymph node dissection for squamous carcinoma of the esophagus is still a matter of debate, and is being addressed in an ongoing nationwide randomized control trial by the Japan Clinical Oncology Group 12…”

Section: Esophageal Surgerymentioning

confidence: 99%

Gastroenterological surgery in Japan: The past, the present and the future

Colvin

Mizushima

Eguchi

et al. 2017

Annals of Gastroent Surgery

Self Cite

138

View full text Add to dashboard Cite

In the last two centuries, there has been remarkable progress in the field of gastroenterological surgery, including the curative resection of cancers, replacement of failed organs through transplantation, increased safety of undergoing major surgeries and decreased operative morbidity through developments in minimal access surgery. Japan has very much been at the forefront of these advances, as is evident from the present review, from advancing the surgical management of gastric cancer to the pioneering work in live‐donor transplantation. This review also highlights many instances where surgical management of the same pathologies has evolved differently between Japan and the West. It is encouraging that many procedures established in Japan are eventually taken up by the West, often after rigorous assessment affirming the quality and applicability of such techniques. In Japan, many of the crucial issues in gastroenterological surgery are increasingly addressed through large multi‐institutional prospective control trials, ensuring that Japanese surgeons continue to contribute to the advances in gastroenterological surgery.

show abstract

Section: Esophageal Surgerymentioning

confidence: 99%

Gastroenterological surgery in Japan: The past, the present and the future

Colvin

Mizushima

Eguchi

et al. 2017

Annals of Gastroent Surgery

Self Cite

138

View full text Add to dashboard Cite

show abstract

“…These pT1 tumors were divided to three groups: pT1a‐EP/LPM (n = 51), pT1a‐MM/pT1b‐SM1 (n = 34), and pT1b‐SM2/SM3 (n = 61) according to the differences in recommended therapy by the Japanese guideline 8. Thus, the mean SUV max for pT1a‐EP/LPM was 1.362 ± 0.890, that for pT1a‐MM/pT1b‐SM1 was 2.453 ± 1.872, and that for pT1b‐SM2/SM3 was 4.265 ± 3.233.…”

Section: Resultsmentioning

confidence: 99%

“…ME‐NBI has recently been used to determine the depth of SCC invasion in Japan 8. ME‐NBI is a diagnostic modality that utilizes pattern recognition of abnormal microvessels.…”

Section: Discussionmentioning

confidence: 99%

“…However, recent developments in gastrointestinal endoscopy have enabled the detection of superficial esophageal cancer, and endoscopic resection (ER), especially endoscopic submucosal dissection (ESD), has become a standard therapeutic modality for mucosal esophageal cancer 4, 5, 6. In Japan, the indication for ER of esophageal cancer is a tumor located within the mucosal epithelium (T1a‐EP [equal to Tis in the TNM classification7]) or lamina propria mucosae (T1a‐LPM) because the incidence of lymph node metastasis is very low (≤5%) 8. The recommended diagnostic modalities are endoscopic ultrasonography (EUS)9 and magnifying endoscopy with narrow band imaging (ME‐NBI) 10.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

¹⁸F‐Fluorodeoxyglucose positron emission tomography can be used to determine the indication for endoscopic resection of superficial esophageal cancer

et al. 2018

Self Cite

View full text Add to dashboard Cite

18F‐Fluorodeoxyglucose positron emission tomography (FDG‐PET) is a useful imaging modality that reflects the tumor activity. However, FDG‐PET is mainly used for advanced cancer, not superficial cancer. In this study, we investigated the relationship between the superficial tumor depth of esophageal cancer and the FDG uptake to determine the indications for endoscopic resection (ER). From 2009 to 2017, 444 patients with esophageal cancer underwent esophagectomy or endoscopic submucosal dissection (ESD), and 195 patients were pathologically diagnosed with superficial cancer. Among them, 146 patients were examined by FDG‐PET before esophagectomy or ESD. In these 146 patients, the relationship between the pathological tumor depth and FDG uptake was analyzed. The mean maximum standardized uptake value in pT1a‐EP/LPM tumors was 1.362 ± 0.890, that in pT1a‐MM/pT1b‐SM1 tumors was 2.453 ± 1.872, and that in pT1b‐SM2/SM3 tumors was 4.265 ± 3.233 (P < .0001). Among 51 pT1a‐EP/LPM tumors, 10 (19.6%) showed positive detection of FDG. For pT1a‐MM/pT1b‐SM1 and pT1b‐SM2/SM3 tumors, the detection rate was 52.9% (18/34) and 82.0% (50/61), respectively. The detection rate of pT1a‐EP/LPM was significantly lower than in the other two groups (P < .0001). Among 10 FDG‐PET‐positive lesions, only 1 had no apparent reason for PET positivity; however, 9 of 10 had a suitable reason for detectability by PET and inadequacy for ER. Negative detection of superficial esophageal squamous cell carcinoma by FDG‐PET is useful to determine the indication for ER when the tumor depth cannot be diagnosed even after performing magnifying endoscopy with narrow band imaging and endoscopic ultrasonography. When FDG uptake is recognized, a therapeutic modality other than ER should be considered.

show abstract

“…Those authors concluded that p53 is the most important candidate biomarker. However, no biomarker, including p53, has yet been widely accepted for clinical application, nor has one been mentioned as useful for predicting chemoradiosensitivity in the Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus in Japan [10]. This is because there is still not sufficient evidence of the usefulness of these biomarkers for that purpose.…”

Section: Introductionmentioning

confidence: 86%

Novel Candidate Biomarkers of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma: A Systematic Review

Sato

Motoyama²,

Saito³

et al. 2016

Eur Surg Res

View full text Add to dashboard Cite

There is no doubt that, along with surgery, chemoradiotherapy is an important treatment for esophageal squamous cell carcinoma (ESCC). Patients who respond well to chemoradiotherapy obtain great benefits toward overcoming their cancer, and so a more favorable prognosis. On the other hand, patients who do not respond well have wasted valuable time and experienced severe toxicity and seriously diminished quality of life, only to have their cancer recur with an unfavorable prognosis. For this reason, a reliable biomarker of chemoradiosensitivity in ESCC has long been sought. In this review, we will enumerate recently reported candidate biomarkers of chemoradiosensitivity in ESCC that have the potential for future clinical application.

show abstract

Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society

Cited by 404 publications

References 0 publications

Gastroenterological surgery in Japan: The past, the present and the future

Gastroenterological surgery in Japan: The past, the present and the future

¹⁸F‐Fluorodeoxyglucose positron emission tomography can be used to determine the indication for endoscopic resection of superficial esophageal cancer

Novel Candidate Biomarkers of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma: A Systematic Review

Contact Info

Product

Resources

About

Guidelines for Diagnosis and Treatment of Carcinoma of the Esophagus April 2012 edited by the Japan Esophageal Society

Cited by 404 publications

References 0 publications

Gastroenterological surgery in Japan: The past, the present and the future

Gastroenterological surgery in Japan: The past, the present and the future

18F‐Fluorodeoxyglucose positron emission tomography can be used to determine the indication for endoscopic resection of superficial esophageal cancer

Novel Candidate Biomarkers of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma: A Systematic Review

Contact Info

Product

Resources

About

¹⁸F‐Fluorodeoxyglucose positron emission tomography can be used to determine the indication for endoscopic resection of superficial esophageal cancer