Guidelines for the Clinical Diagnosis of Lyme Disease

McCaulley, Mark E.

doi:10.7326/0003-4819-129-5-199809010-00017

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“…Unfortunately, such tests are prone to misdiagnosis of Lyme disease, despite the introduction of a two‐step protocol including a second test (Western blot) to confirm a positive or indeterminate enzyme‐linked immunosorbent assay (ELISA) or immunofluorescence assay [4,5]. In particular, false‐negative ELISA results may be recorded in patients with a diagnostic Western blot, thus limiting the validity of this assay format [6,7].…”

Section: Introductionmentioning

confidence: 99%