Guidelines on Postoperative Care

Tufano, R; Leone, Denise Rocha Raimundo

doi:10.1007/978-88-470-2296-6_59

Cited by 1 publication

(1 citation statement)

References 10 publications

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“…Fifteen studies were excluded after reading the full paper (Avila 1991;Bagan 1998;Berti 2000;Gallardo 1982;Giudice 1987;Jimenez-Martinez 2004;Kantor 1984;Letarget 1998;Lobo 1983;Olmedo 2001;Perez 2002;Schreiber 1998;Sunshine 1986;Tufano 1981;Zapata 2000).…”

Section: Description Of Studiesmentioning

confidence: 99%

Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults

Barden¹,

Derry²,

McQuay³

et al. 2008

Cochrane Database of Systematic Reviews

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Background-Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions. Dexketoprofen is the (S)-enantiomer, which is believed to confer analgesia. Theoretically dexketoprofen is expected to provide equivalent analgesia to ketoprofen at half the dose, with a consequent reduction in gastrointestinal adverse events. Objectives-To assess efficacy, duration of action, and associated adverse events of single dose oral ketoprofen and dexketoprofen in acute postoperative pain in adults. Search methods-We searched Cochrane CENTRAL, MEDLINE, EMBASE and the Oxford Pain Relief Database for studies to August 2009. Selection criteria-Randomised, double blind, placebo-controlled trials of single dose orally administered ketoprofen and dexketoprofen in adults with moderate to severe acute postoperative pain. Data collection and analysis-Two review authors independently assessed trial quality and extracted data. Pain relief or pain intensity data were extracted and converted into the dichotomous outcome of number of participants with at least 50% pain relief over 4 to 6 hours, from which

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