Guidelines on sodium lauryl sulfate (SLS) exposure tests

Tupker, Ron A.; Willis, Carolyn M.; Berardesca, Enzo; Ch, Lee; Fartasch, Manigé; Agner, Tove; Serup, J

doi:10.1111/j.1600-0536.1997.tb00041.x

Cited by 244 publications

(98 citation statements)

References 108 publications

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“…Specifying exact and small skin areas for repeated measurements within clinical research is therefore necessary [11,12,13,15]. Furthermore, several skin parameters are usually obtained to achieve a comprehensive picture of the skin barrier function and possible treatment effects [6,9,16,17]. It is known that even slight manipulations like placing a probe or a camera head on the skin surface influence the skin function (e.g.…”

Section: Introductionmentioning

confidence: 99%

Do Repeated Skin Barrier Measurements Influence Each Other's Results? An Explorative Study

Kottner

Ludriksone²,

Bartels³

et al. 2013

Skin Pharmacol Physiol

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Background: Biophysical skin measurement techniques are widely used to quantify the skin barrier function. In clinical research usually several parameters are subsequently measured in the same skin areas. In this study, possible interfering effects of subsequent measurement procedures on transepidermal water loss (TEWL), stratum corneum hydration (SCH) and skin surface pH were investigated. Methods: An exploratory study was conducted. Twelve young (mean age 32.9 ± 7.2 years) and 12 elderly (mean age 68.3 ± 2.5 years) subjects without any skin diseases were enrolled. The parameters TEWL, skin surface pH, SCH, sebum content, and surface evaluation of living skin were obtained successively in pairs from 4 contralateral volar forearm skin areas. Results: SCH and skin surface pH seemed to be unaffected by previous measurement procedures. TEWL was systematically increased after pH and systematically decreased after stratum corneum measurements. Conclusions: Measurements per se might interact with the skin, thus changing its characteristics. If several skin barrier function parameters need to be assessed subsequently in the same skin areas, we recommend that TEWL should be measured first followed by all others.

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Section: Introductionmentioning

confidence: 99%

Do Repeated Skin Barrier Measurements Influence Each Other's Results? An Explorative Study

Kottner

Ludriksone²,

Bartels³

et al. 2013

Skin Pharmacol Physiol

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“…A 2% concentration of SLS in distilled water (high purity 99% from Henkel KOGA, Düsseldorf, Germany) was used according to recently published guidelines [13]. This concentration was chosen because previous tests had shown that the irritant produced a response possible to judge by a visual score.…”

Section: Methodsmentioning

confidence: 99%

Instrumental Measurement of the Mantoux Test: Differential Effects of Tuberculin and Sodium Lauryl Sulphate on Impedance Response Patterns in Human Skin

Nyrén

Hagströmer²,

Emtestam³

2000

Dermatology

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Background and Objective: The tuberculin (PPD) test is a model reaction for the cell-mediated immune system of the skin. The aim of this study is to compare the non-invasive technique based on electrical impedance for investigation of the tuberculin test with an irritant contact reaction induced by sodium lauryl sulphate, which has already been carefully evaluated using this method. Methods: 0.1 ml of PPD (2 TU) was injected intracutaneously into the volar forearms of 20 adult healthy subjects, all known to be tuberculin sensitized. Assessments were performed 3 and 7 days after the injections, using visual scoring, a new electrical impedance technique and transepidermal water loss (TEWL). Results: In the 16 cases that completed the study, compared to relevant controls and reactions induced by sodium lauryl sulphate statistically significant changes in 3 of the 4 impedance indices were found: both the means of index MIX and index IMIX increased (p ≤ 0.01) and the mean of index PIX decreased (p ≤ 0.05). Furthermore, similar impedance response patterns occurred in another cell- mediated immune reaction that we have studied previously – namely, the allergic contact reaction induced by nickel sulphate. Unlike the irritant reactions, no significant increase in TEWL values in tuberculin reactions were found. This can be explained by the fact that the epidermis is little affected, since the inflammatory process in the tuberculin reaction is located more deeply in the dermis than with the irritant reaction. Conclusion: The current study strongly indicates that electrical impedance in the described version, besides contact dermatitis, also seems suitable for studies of the tuberculin reaction. This will add a new indication for the technique, and studies of further clinical applications are in progress.

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“…Tupker et al [106] studied the detergent sodium lauryl sulfate, normally used to induce contact irritant dermatitis, which induced dose-related stinging pain, vasodilatation and pronounced prostaglandin E2 release after infusion. In a study of UV-B-irradiated skin, infusion of both bradykinin B1 and B2 agonists enhanced the pain sensation and axon reflex vasodilatation.…”

Section: Retrodialysis In Experimental Human Studiesmentioning

confidence: 99%

Retrodialysis: A Review of Experimental and Clinical Applications of Reverse Microdialysis in the Skin

Melgaard

Hersini

Gazerani

et al. 2013

Skin Pharmacol Physiol

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Microdialysis is a method that has been used for decades to recover endogenous mediators, metabolites and drugs from the interstitial space in several tissues of both animals and humans. The principle of microdialysis is the flux of compounds across a semipermeable membrane. The application of microdialysis as a method of drug delivery is a process referred to as retrodialysis, i.e. the introduction of a substance into the extracellular space via a microdialysis probe. Thus, microdialysis also offers opportunities to deliver mediators and drugs to target tissues by adding solutes to the perfusion medium. In this context, retrodialysis combines a method for minimally invasive delivery with a sampling method to study biological processes in health and disease. The aim of this review is to give insight into the use of retrodialysis by outlining examples of retrodialysis studies focusing on applications in skin in animal studies, human experimental investigations and clinical settings.

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Guidelines on sodium lauryl sulfate (SLS) exposure tests

Cited by 244 publications

References 108 publications

Do Repeated Skin Barrier Measurements Influence Each Other's Results? An Explorative Study

Do Repeated Skin Barrier Measurements Influence Each Other's Results? An Explorative Study

Instrumental Measurement of the Mantoux Test: Differential Effects of Tuberculin and Sodium Lauryl Sulphate on Impedance Response Patterns in Human Skin

Retrodialysis: A Review of Experimental and Clinical Applications of Reverse Microdialysis in the Skin

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