2016
DOI: 10.1002/jmv.24620
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Guillain–Barré syndrome following acute co‐super‐infection of hepatitis E virus and cytomegalovirus in a chronic hepatitis B virus carrier

Abstract: Guillain-Barré syndrome (GBS) is a rare neurological complication of hepatitis B. GBS presence in acute hepatitis E virus (HEV) and cytomegalovirus (CMV) infection is also sporadically reported. Here, a rare case of GBS in a chronic Hepatitis B virus carrier co-infected with HEV and CMV was reported. Based on the analysis on the progress of the manifestations and virus serological detection results, it could be concluded that GBS might mostly likely result from super-infection of HEV and CMV. This case report … Show more

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Cited by 13 publications
(6 citation statements)
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“…Despite an outbreak of 1989 was cause by GT1 HEV in Xinjiang province, China, the predominant circulating genotype in China has shifted towards GT4 over the decades, with occasional GT1 cases [ [16] , [17] , [18] , [19] , [20] ]. Several sporadic cases of neurological injury that possibly linked to HEV infection have been documented in China [ 12 , [21] , [22] , [23] ]. However, these cases were either coinfected with other pathogens, such as hepatitis B virus and cytomegalovirus [ 21 ], or only positive for anti-HEV IgM [ 12 , 22 , 23 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Despite an outbreak of 1989 was cause by GT1 HEV in Xinjiang province, China, the predominant circulating genotype in China has shifted towards GT4 over the decades, with occasional GT1 cases [ [16] , [17] , [18] , [19] , [20] ]. Several sporadic cases of neurological injury that possibly linked to HEV infection have been documented in China [ 12 , [21] , [22] , [23] ]. However, these cases were either coinfected with other pathogens, such as hepatitis B virus and cytomegalovirus [ 21 ], or only positive for anti-HEV IgM [ 12 , 22 , 23 ].…”
Section: Discussionmentioning
confidence: 99%
“…Several sporadic cases of neurological injury that possibly linked to HEV infection have been documented in China [ 12 , [21] , [22] , [23] ]. However, these cases were either coinfected with other pathogens, such as hepatitis B virus and cytomegalovirus [ 21 ], or only positive for anti-HEV IgM [ 12 , 22 , 23 ]. Although there was one case of GT4 HEV related bilateral peripheral facial palsy reported in Japan [ 24 ], the causation with HEV infection is uncertain.…”
Section: Discussionmentioning
confidence: 99%
“…Among the neuro-muscular manifestations, the commonly reported were neuralgic amyotrophy (n = 102/179; 56.98%) [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] and Guillain-Barré syndrome (n = 36/179; 20.11%) [10,[24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40]. The other rarer neurological manifestations that were reported include mononeuritis multiplex [10], encephalitis [11,13,39,41], cerebral ischemia [11,39], myasthenia gravis [42], polyneuromyopathy [24,43], meningo-radiculitis [10,44], epilepsy [11], encephalopathy [45], facial nerve palsy…”
Section: Neurological and Musculoskeletal Manifestationsmentioning
confidence: 99%
“…GBS due to hepatitis A is rare and has been reported in a few case reports with relatively good outcomes [2]. Coinfection with bacterial or viral agents has been reported, and thus, evaluation for concomitant infection should be conducted [3]. e patient in the case was ruled out for influenza and COVID-19.…”
Section: Discussionmentioning
confidence: 99%