Guillain-Barré syndrome in pregnancy: An unusual case

Zafar, Mir Sadaqat Hassan; Naqash, Mohd Mubarik; Bhat, Tariq A.; Malik, Ghaus M.

doi:10.4103/2249-4863.109965

Cited by 26 publications

(18 citation statements)

References 7 publications

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“…[ 2 ] Delayed diagnosis is common in pregnancy or immediate postpartum period because the initial non-specific symptoms may mimic changes in the pregnancy. [ 3 ] The relation between GBS and pregnancy or delivery is of special interest because of the dramatic character of GBS symptoms in a woman facing delivery. The purpose of this study was to quantity the risk of GBS for the mother during the pregnancy and postpartum periods and look for correlation between pregnancy and GBS.…”

Section: Introductionmentioning

confidence: 99%

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Sharma

Hussain

et al. 2015

Ann Indian Acad Neurol

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Background:Guillain-Barré syndrome (GBS) is rare in pregnancy with an estimated incidence between 1.2 and 1.9 cases per 100,000 people annually, and it is generally accepted that it carries a high maternal risk. Most reports of GBS with pregnancy are case reports only.Aim:Purpose of this retrospective study was to find the correlation between pregnancy and GBS.Settings and Design:Records of patients admitted in neurology division were analyzed in a tertiary care teaching hospital in the northeastern Indian pregnant female population with GBS between 15-49 years during the period of 2009-2013.Materials and Methods:We analyzed the records of 47 patients with pregnancy and GBS, evaluated and treated in our institute from August 2009 to December 2013. This is retrospective observational study done in North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), India.Result:Predominant form of GBS was acute inflammatory demyelinating polyneuropathy (AIDP). The weakness started from the lower limbs in majority of patients. Ten percent of women had bifacial weakness. Most of patients had good maternal and fetal outcome. Two patients received intravenous immunoglobulin (IVIG). Only two patient required ventilator supports and one patient had intrauterine death (IUD) and died due to respiratory failure.Conclusion:Our results indicate that risk of GBS increases in third trimester and first 2 weeks after delivery. Demyelinating variety of GBS was common in our population. GBS natural course during pregnancy is mild and showed quick recovery. Maternal and perinatal outcome was good.

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Section: Introductionmentioning

confidence: 99%

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Sharma

Hussain

et al. 2015

Ann Indian Acad Neurol

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“…Maternal mortality is usually due to respiratory complications and perinatal due to preterm labor and delivery. [ 6 ]…”

Section: Discussionmentioning

confidence: 99%

“…Delayed diagnosis during pregnancy and immediate postpartum period is possible due to initial nonspecific symptoms which may mimic changes in pregnancy. [ 6 ]…”

Section: Discussionmentioning

confidence: 99%

Guillain-Barré syndrome in pregnancy: A conservatively managed case

Fernando¹,

Ambanwala²,

Ranaweera

et al. 2016

J Family Med Prim Care

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Guillain–Barré syndrome (GBS) is an autoimmune disease. Estimated population incidence ranges from 0.62 to 2.66 cases per 100,000 person-years across all age groups. We report a case of GBS in a 22-year-old primigravida who presented at 36 weeks of the period of gestation (POG), with complaints of bilateral progressive lower limb numbness and weakness for 2 weeks duration. Magnetic resonance imaging of the brain was done to exclude other possible causes. Diagnosis of GBS was made according to the Brighton criteria, which our patient falls into Level 2. She received intensive care management. The patient improved rapidly without any specific management. She went to labor spontaneously and delivered a healthy baby with a birth weight of 2.8 kg at 38 weeks of POG. She continued to receive supportive therapy and improved significantly.

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“…Nearly all these cases, however, occurred in the second or third trimester or the first month postpartum. Delayed diagnosis is common in pregnancy or immediate postpartum period because the initial symptoms can be non-specific [3]. GBS treatment in pregnancy is either a course of plasma exchange or intravenous immunoglobulins, just as in the rest of general population [4].…”

Section: Introductionmentioning

confidence: 99%

Uncommon case of Guillain-Barré Syndrome in Young Female in the First Trimester of Pregnancy

Wiszniewska¹

2017

OGIJ

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Background: Guillain-Barré syndrome (GBS) is an autoimmune disorder with the estimated incidence between 1.2 and 1.9 cases per 100 000 people annually. It is rare in pregnancy as there is a decrease in the cell-mediated immunity, but it is generally accepted that it carries a high maternal risk. Aim: In this study, a case of an 18-year-old pregnant woman suffering from GBS who presented with flaccid quadriplegia is discussed in the aspects of diagnosis, treatment, and outcome. Conclusion: Rapid recognition of GBS as well as resolute and prompt treatment consisting of plasma exchange and intravenous immunoglobulins (IVIG) are necessary to get a good outcome in pregnant women such as the patient discussed.

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Guillain-Barré syndrome in pregnancy: An unusual case

Cited by 26 publications

References 7 publications

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Guillain-Barré syndrome complicating pregnancy and correlation with maternal and fetal outcome in North Eastern India: A retrospective study

Guillain-Barré syndrome in pregnancy: A conservatively managed case

Uncommon case of Guillain-Barré Syndrome in Young Female in the First Trimester of Pregnancy

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