Gut health promoting activity of new putative probiotic/protective Lactobacillus spp. strains: A functional study in the small intestinal cell model

Nissen, Lorenzo; Chingwaru, Walter; Sgorbati, Barbara; Biavati, Bruno; Cencič, Avrelija

doi:10.1016/j.ijfoodmicro.2009.08.027

Cited by 88 publications

(70 citation statements)

References 37 publications

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“…72 As noted in other studies with prebiotics and probiotics, effects on gut barrier function varied among strains and effector molecules. [73][74][75] While intestinal permeability may be altered in a subset of IBS patients, the relationship with dysbiosis requires further study. Commensal and probiotic organisms can regulate intestinal barrier function through a variety of mechanisms and hence contribute to the development or perpetuation of IBS.…”

Section: Conclusion and Future Researchmentioning

confidence: 99%

The intestinal microbiome, probiotics and prebiotics in neurogastroenterology

Saulnier¹,

et al. 2013

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The brain-gut axis allows bidirectional communication between the central nervous system (CNS) and the enteric nervous system (ENS), linking emotional and cognitive centers of the brain with peripheral intestinal functions. Recent experimental work suggests that the gut microbiota have an impact on the brain-gut axis. A group of experts convened by the International Scientific Association for Probiotics and Prebiotics (ISAPP) discussed the role of gut bacteria on brain functions and the implications for probiotic and prebiotic science. The experts reviewed and discussed current available data on the role of gut microbiota on epithelial cell function, gastrointestinal motility, visceral sensitivity, perception and behavior. Data, mostly gathered from animal studies, suggest interactions of gut microbiota not only with the enteric nervous system but also with the central nervous system via neural, neuroendocrine, neuroimmune and humoral links. Microbial colonization impacts mammalian brain development in early life and subsequent adult behavior. These findings provide novel insights for improved understanding of the potential role of gut microbial communities on psychological disorders, most particularly in the field of psychological comorbidities associated with functional bowel disorders like irritable bowel syndrome (IBS) and should present new opportunity for interventions with pro-and prebiotics.

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Section: Conclusion and Future Researchmentioning

confidence: 99%

The intestinal microbiome, probiotics and prebiotics in neurogastroenterology

Saulnier¹,

et al. 2013

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“…When comparing L.plantarumwith its bacteriocins's antibacterial activity, it showed to be not affected by low temperatures, since its antibacterial activity is not altered at -20 °C. Nissen et al (2009) in vitro experiment showed that immune system responses, intestinal integrity enhancement, and intestinal metabolic activity can highly be stimulated by L. plantarum. In addition, epithelial cells are proven to be protected by L. plantarum from E. coli-induced damage, per Qin et al (2009).…”

Section: Antagonism Effectmentioning

confidence: 99%

Isolation, identification and characterization of Lactobacillus plantarum from camel milk and its antagonist effect against diarrheal bacteria.

Toualbia

Koiche²

2018

Emir J Food Agric

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The main objective of this study is to define probiotic bacteria efficiency against bacterial infantile diarrhea. Lactic acid bacteria (LAB) was used as a natural resource and extracted of camel milk from southern Algeria. The isolation was followed by molecular identification using the 16S rDNA sequencing method. One hundred and fifty fecal samples were collected over 18 months from children suffering from diarrhea and aged 2 years or under. Identification results reveal the isolated lactic bacteria as Lactobacillus plantarum. In the other side, a total of 120 fecal samples were positive for bacterial growth, these pathogenic bacteria were identified as: Escherichia fergusonii (92%), Salmonella enterica subsp. Diarizonae (7.33%) and Proteus mirabilis (0.66%). The inhibitory effect study of lactic acid bacteria on pathogenic bacteria shows varying effects of L. plantarum in relation to the various pathogenic isolates, mentioning that the most important effect was expressed against Escherichia fergusonii with 22 mm. All the results allow us to classify that camel's milk is a natural source rich in lactic acid bacteria, in particular L. plantarum, with an inhibitory ability against the pathogenic bacteria responsible for diarrhea. Therefore L. plantarum produces bioactive molecules responsible for this effect.

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“…Penggunaan Lactobacillus plantarum untuk pengobatan irritable bowel syndrome telah teruji, terdapat bukti bahwa mikroba ini mengurangi rasa sakit, mencegah konstipasi dan kembung (Bixquert, 2009). Nissen et al (2009), memperlihatkan secara in vitro bahwa L. plantarum dapat memperkuat integritas usus, serta aktivitas metabolik sel usus dan menstimulasi respon imun.…”

Section: Pendahuluanunclassified

Lactobacillus plantarum PADA FESES INDIVIDU DEWASA SEHAT YANG MENGONSUMSI Lactobacillus plantarum IS-10506 DARI DADIH

Adib

Wahid

Sudarmono

et al. 2013

jtip

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A placebo double blind pre-post human study was conducted in apparently healthy adults. There were two treatment groups consisting of Group A and B representing probiotic and placebo group, respectively ABSTRAKPenelitian ini menggunakan placebo double blind pre-post treatment design, yang dilakukan pada subjek individu dewasa sehat. Terdapat 2 kelompok perlakuan yang terdiri atas kelompok A dan B, yaitu kelompok perlakuan yang diberikan probiotik Lactobacillus plantarum IS-10506 dan kontrol (plasebo). Dua puluh empat orang telah dipilih secara acak, masing-masing diberi plasebo atau probiotik Lactobacillus plantarum IS-10506. Bubuk kering dalam wadah kapsul diberikan sebagai suplemen dengan dosis 2.6x10 10 CFU/hari selama 21 hari berturut-turut. Sampel feses diambil sebelum dan sesudah suplemen diberikan. Sampel feses segar dikultur pada media MRS dan dilakukan hitung jumlah bakteri secara konvensional (plate count) untuk mengetahui viabilitas Lactobacillus sp. Sebagian sampel dibekukan untuk pemeriksaan real time PCR untuk melihat keberadaan Lactobacillus plantarum IS-10506 dengan primer spesifik. Keberadaan Lactobacillus sp pada feses orang dewasa sehat yang diberi kapsul berisi probiotik Lactobacillus plantarum IS-10506 lebih banyak secara signifikan dibandingkan individu yang diberi bubuk plasebo. Deteksi molekuler mengkonfirmasi dan memvalidasi bahwa Lactobacillus plantarum IS-10506 berada dalam feses kelompok probiotik setelah pemberian suplemen selama 21 hari. Namun, keberadaan dan viabilitas Lactobacillus plantarum IS-10506 tidak ditemukan secara konsisten dalam saluran cerna.

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Gut health promoting activity of new putative probiotic/protective Lactobacillus spp. strains: A functional study in the small intestinal cell model

Cited by 88 publications

References 37 publications

The intestinal microbiome, probiotics and prebiotics in neurogastroenterology

The intestinal microbiome, probiotics and prebiotics in neurogastroenterology

Isolation, identification and characterization of Lactobacillus plantarum from camel milk and its antagonist effect against diarrheal bacteria.

Lactobacillus plantarum PADA FESES INDIVIDU DEWASA SEHAT YANG MENGONSUMSI Lactobacillus plantarum IS-10506 DARI DADIH

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