2024
DOI: 10.3390/nu16071025
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Gut–Liver Axis Dysregulation in Portal Hypertension: Emerging Frontiers

Martina Lombardi,
Jacopo Troisi,
Benedetta Maria Motta
et al.

Abstract: Portal hypertension (PH) is a complex clinical challenge with severe complications, including variceal bleeding, ascites, hepatic encephalopathy, and hepatorenal syndrome. The gut microbiota (GM) and its interconnectedness with human health have emerged as a captivating field of research. This review explores the intricate connections between the gut and the liver, aiming to elucidate how alterations in GM, intestinal barrier function, and gut-derived molecules impact the development and progression of PH. A s… Show more

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