Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection

Moore, Makala L.; Ford, Jermaine L.; Schladweiler, Mette C.; Dye, Janice A.; Jackson, Thomas W.; Miller, Colette N.

doi:10.1007/s11306-024-02099-x

Metabolomics

2024

DOI: 10.1007/s11306-024-02099-x

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Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection

Makala L. Moore,

Jermaine L. Ford,

Mette C. Schladweiler

et al.

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Cited by 1 publication

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Diagnosing and engineering gut microbiomes

Cappio Barazzone,

Diard,

Hug

et al. 2024

EMBO Mol Med

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The microbes, nutrients and toxins that we are exposed to can have a profound effect on the composition and function of the gut microbiome. Thousands of peer-reviewed publications link microbiome composition and function to health from the moment of birth, right through to centenarians, generating a tantalizing glimpse of what might be possible if we could intervene rationally. Nevertheless, there remain relatively few real-world examples where successful microbiome engineering leads to beneficial health effects. Here we aim to provide a framework for the progress needed to turn gut microbiome engineering from a trial-and-error approach to a rational medical intervention. The workflow starts with truly understanding and accurately diagnosing the problems that we are trying to fix, before moving on to developing technologies that can achieve the desired changes.

show abstract

Diagnosing and engineering gut microbiomes

Cappio Barazzone,

Diard,

Hug

et al. 2024

EMBO Mol Med

View full text Add to dashboard Cite

show abstract

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Gut metabolic changes during pregnancy reveal the importance of gastrointestinal region in sample collection

Cited by 1 publication

References 71 publications

Diagnosing and engineering gut microbiomes

Diagnosing and engineering gut microbiomes

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