Crohn’s Disease - The Current State of the Art 2023
DOI: 10.5772/intechopen.110768
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Gut Microbiome and Crohn’s Disease: An Enigmatic Crosstalk

Abstract: Crohn’s disease (CD) is a chronic, recurrent, immune-mediated inflammatory bowel disease that demonstrates a spectrum of intestinal and extra-intestinal manifestations. The pathogenesis of CD is multifactorial and involves a complex interplay between environmental and microbiological factors in a genetically susceptible host. There is robust evidence suggesting the role of gut microbial dysbiosis in the development as well as exacerbation of CD by immune dysregulation and alteration in the immune microbiota cr… Show more

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