Gut Microbiome Modulation of Glutamate Dynamics: Implications for Brain Health and Neurotoxicity
Benjamin F. Gruenbaum,
Kiran S. Merchant,
Alexander Zlotnik
et al.
Abstract:The gut–brain axis plays an integral role in maintaining overall health, with growing evidence suggesting its impact on the development of various neuropsychiatric disorders, including depression. This review explores the complex relationship between gut microbiota and glutamate (Glu) regulation, highlighting its effect on brain health, particularly in the context of depression following certain neurological insults. We discuss how microbial populations can either facilitate or limit Glu uptake, influencing it… Show more
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