GW27-e0271 A study on the mechanism of the oxidative damage in Ginsenoside Rb1 against the intrinsic aging of mouse brain

Zhou, Bin; Yu, Sungwook; Yu, Xianguan; Liu, Yong; Liu, Dinghui; Wu, Lin; Wang, Min; Ling, Yesheng; Hao, Baoshun; Chen, Lin; Qian, Xiaoxian

doi:10.1016/j.jacc.2016.07.040

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Panax Ginseng C a Meyer And Its Compounds Delay Cellular Agi...1

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2023

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“…Ginsenoside Rb1 can delay replicating endothelial cells by inhibiting NF-κB-p65-mediated inflammatory responses. Aging, reducing inflammatory factor IL-6, TNF-α levels, and NF-κB-p65 activity [223]. It can also play the role of anti-radiation injury-induced HSC/HPC aging by regulating the SIRT6/NF-κB signaling pathway [224].…”

Section: Panax Ginseng C a Meyer And Its Compounds Delay Cellular Agi...mentioning

confidence: 99%

Traditional herbs: mechanisms to combat cellular senescence

Wang,

Yang

et al. 2023

Aging

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Cellular senescence plays a very important role in the ageing of organisms and age-related diseases that increase with age, a process that involves physiological, structural, biochemical and molecular changes in cells. In recent years, it has been found that the active ingredients of herbs and their natural products can prevent and control cellular senescence by affecting telomerase activity, oxidative stress response, autophagy, mitochondrial disorders, DNA damage, inflammatory response, metabolism, intestinal flora, and other factors. In this paper, we review the research information on the prevention and control of cellular senescence in Chinese herbal medicine through computer searches of PubMed, Web of Science, Science Direct and CNKI databases.

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Section: Panax Ginseng C a Meyer And Its Compounds Delay Cellular Agi...mentioning

confidence: 99%