Gynecological Carcinosarcomas

Berton‐Rigaud, Dominique; Frenel, J. S.; Devouassoux‐Shisheboran, Mojgan; Ray‐Coquard, Isabelle

doi:10.1007/978-3-319-32110-3_17

Cited by 2 publications

(4 citation statements)

References 33 publications

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“…[217][218][219][220] Most pathologists now consider MMMTs to be a variant of poor-risk, poorly differentiated epithelial ovarian cancer (metaplastic carcinoma). 221 Patients with MMMTs are not candidates for fertility-sparing surgery regardless of age. The staging system for ovarian and primary peritoneal cancer is also used for MMMTs (see Table 1 in the complete version of these guidelines [ST-1]).…”

Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

“…Patients with stage I to IV MMMT may be treated as per epithelial ovarian cancer (see OV-3; page 1138). 221,[225][226][227][228][229][230] The intraperitoneal chemotherapy regimen described for ovarian cancer can be used for select patients with MMMT. For the 2016 update, the NCCN Panel also added 3 new postoperative chemotherapy options for patients with stage I to IV MMMT: cisplatin/ifosfamide (category 2A), carboplatin/ifosfamide (category 2A), and paclitaxel/ ifosfamide (category 2B).…”

Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

“…For the 2016 update, the NCCN Panel also added 3 new postoperative chemotherapy options for patients with stage I to IV MMMT: cisplatin/ifosfamide (category 2A), carboplatin/ifosfamide (category 2A), and paclitaxel/ ifosfamide (category 2B). 217,221,225,231 After treatment, the surveillance and follow-up recommendations for epithelial ovarian cancer are also used for MMMTs.…”

Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

See 2 more Smart Citations

Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology

Morgan

Armstrong

Alvarez

et al. 2016

J Natl Compr Canc Netw

307

233

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Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

Section: Carcinosarcomas (Mmmts)mentioning

confidence: 99%

See 1 more Smart Citation

Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology

Morgan

Armstrong

Alvarez

et al. 2016

J Natl Compr Canc Netw

307

233

View full text Add to dashboard Cite

“…Prognosis for localized stage disease is poor with a high risk of recurrences with an overall median survival of less than 2 years. Carcinosarcomas are known to be metaplastic carcinomas and should be treated as endometrial or ovarian high-risk carcinomas (1).…”

Section: Introductıonmentioning

confidence: 99%

Transthoracic Transdiaphragmatic Resection for Liver Metastasis of Ovarian Carcinosarcoma with Invasion of Right Hemidiaphragm and Lung.

Çakmak¹,

Karaman²,

Çetin³

et al. 2015

Acta Oncol Tur.

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ÖZETKolorektal ve nöroendokrin tümörlerde hepatik metastazektominin klinik faydası çok iyi tanımlanmış olmasına karşın, diğer tümörlerinde bu uygulamanın yeri çok net değildir. Bu yazıda over karsinosarkomuna bağlı sağ hemidiafragma ve sağ akciğer alt lobunu invaze etmiş karaciğer metastazlı bir olgu sunmaktayız. Bu olguya abdominal girişim uygulanmadan transtorasik olarak yaklaşılmış ve sağ hemidiafragma, akciğer ve karaciğer rezeksiyonu uygulanmıştır. Hasta bu cerrahi girişim sonrası ortalama 2,5 yıl (27 ay) yaşamıştır. Primer jinekolojik malignitelere bağlı uzak organ metastazlarında da, düşük morbidite ve mortalite oranları ve sağ kalımı uzaması nedeniyle senkron hepatik ve pulmoner metastazektomi uygulanabilir. Bu alanda kısıtlı tecrübeler olmasına rağmen özellikle subdiafragmatik karaciğer ile sağ akciğere olan metastazlarda, transtorasik senkron pulmoner ve hepatik metastazektomi akılda tutulmalıdır. Anahtar Kelimeler: Over karsinosarkomu, senkron, karaciğer, akciğer, metastazektomi ABSTRACT Although hepatic metastasectomy is well established for colorectal and neuroendocrine tumors, the treatment of hepatic metastases from other sites is not well defined. We present a case of ovarian carcinosarcoma with liver metastasis that invaded the right hemidiaphragm and lower lobe of right lung. En bloc transthoracic lung, right hemidiaphragm and liver resection was performed without using an abdominal incision. The patient survived nearly 2.5 years (27 months) after this surgery. Synchronous hepatic and pulmonary metastasectomies can be recommended for the metastatic tumors from the primary gynecologic malignancies. This procedure can be done with low morbidity, mortality rates and prolonges survival. Inspite of the limited experience, the choice of transthoracic synchronous pulmonary and hepatic metastasectomy should be remembered for the patients with subdiapragmatic liver and right sided lung metastasis.

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Gynecological Carcinosarcomas

Cited by 2 publications

References 33 publications

Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology

Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology

Transthoracic Transdiaphragmatic Resection for Liver Metastasis of Ovarian Carcinosarcoma with Invasion of Right Hemidiaphragm and Lung.

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