Background: Adolescence is a transient and dynamic period characterised by several changes in the child’s body and mind. Onset of menarche is major physiological milestone in adolescent girls which is often associated with menstrual irregularities and other hormonal events. Aim of the present study was to evaluate the profile of adolescent girls attending the outpatient clinic.Methods: This hospital based cross-sectional, prospective, observational study was conducted at Bafna hospital from January 2019 to December 2020. We analysed 220 consecutive adolescent girls with gynaecological health issues. The data was collected and analysed using pre-designed questionnaire.Results: Menstrual disorders (64.5%) were most common followed by teenage pregnancies (20.9%). Other complaints included vulvar disorders, breast diseases, genital trauma, hirsuitism, UTI and psychological problems. Anemia (28.1%) and PCOS (30.9%) were also diagnosed. Hormonal treatment was offered to 59.5% girls whereas surgical intervention done in 4% for various indications.Conclusions: Menstrual disorders, teenage pregnancies, PCOS and anemia were the most common issues seen. Adolescent gynaecological problems are unique and specific regarding presentation, diagnosis and treatment options. It is important to tackle them on top priority due to its impact on future reproductive health.