Abstract:Hydrogen sulfide (H 2 S) is an endogenously gaseous messenger with a number of physiological effects. Pharmacological and genetic models point toward an important role for this vasodilator gas in the regulation of vascular tone, cardiac response to ischemia/reperfusion injury, and inflammation among others. Understanding the complex interaction of H 2 S with basic cellular signaling and its impact on endothelial and smooth muscle physiology may provide insights into the early stages of developing vascular infl… Show more
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