Haemangiopericytoma of the mandible

Incidentally diagnosed haemangiopericytoma of the hard palate

“…The more bland lesions with minimal mitotic activity are treated by wide local excision, but the more active and dysplastic lesions are treated by radical surgical excision, with or without adjunctive radiotherapy (10). A chemotherapeutic protocol of cisplatin, cyclophosphamide, adriamycin and vincristine in the treatment of congenital HPC cases (12)(13)(14) and interpheron alpha therapy in the treatment of unresectable HPC cases have been also advocated. Thiele et al (13) suggested that radical surgical removal of the tumour, followed by an adjuvant external-beam radiation therapy with a local dose of 56 to 66 Gy seems to improve patients' outcome, especially with larger lesions, positive surgical margins and high-grade malignant lesions.…”

“…A chemotherapeutic protocol of cisplatin, cyclophosphamide, adriamycin and vincristine in the treatment of congenital HPC cases (12)(13)(14) and interpheron alpha therapy in the treatment of unresectable HPC cases have been also advocated. Thiele et al (13) suggested that radical surgical removal of the tumour, followed by an adjuvant external-beam radiation therapy with a local dose of 56 to 66 Gy seems to improve patients' outcome, especially with larger lesions, positive surgical margins and high-grade malignant lesions. However, in a study of Carew et al (14), the For Peer R relationship between mitosis rate and patient's survival could not be confirmed.…”

“…It accounts for 3% of all tumors in the head and neck (2)(3)(4). About 15-20% of HPC cases have been reported in the head and neck region (4), including: the orbit, nasal cavity, paranasal sinuses, nasopharynx, temporal bone, anterior skull, ear, buccal mucosa, lip, floor of the mouth, gingiva, mandible, salivary gland, larynx and tongue (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15).…”

“…HPC of the oral cavity has been reported in the floor of the mouth, gingiva, alveolar-buccal sulcus, mandible and palate (3,(12)(13)(14)(15). It can occur in any age group, but the most affected age is the fifth and sixth decades (3).…”

Unrecognized hemangiopericytoma of posterior cervical region with intracranial extension

“…Hemangiopericytomas of the head and neck account for nearly 20% of all cases (Auguste et al, 1982), and most commonly arise from the soft tissues in the orbit and in tissues around the oral cavity, nose, nasopharynx, pharynx and neck (Enzinger and Smith, 1976, Abdel-Fattah et al, 1990, Volpe et al, 1991and Billings et al, 2000. A hemangiopericytoma arising from the skull base, temporal bone, mandible and lesions in posterior neck region are uncommon (Abdel-Fattah et al, 1990, Austin and Mills, 1986, Chin et al, 1993, Thiele et al, 2010and Birzgalis et al 1990). This neoplasm clinically behaves aggressively and has a tendency to recur and metastasize (Guthrie et al, 1989 andJääskeläinen et al, 1985).…”