During the three years period of study twelve cross bred cattle were identified that they were suffering with clinical Trypanosomiasis. Up on clinical examination cattle had anorexia, fever, ocular discharges, dullness and enlarged lymph nodes. Stained peripheral blood examination revealed the presence of Trypanosoma evansi. Haematological abnormalities include decreased TEC, PCV, Hb and TLC values (P<0.01). The present leucopaenia was characterized by neutrophilia, eosinophilia and lymphocytopaenia (P>0.05).