Haematological indices of malaria patients coinfected with HIV in Umuahia

Abstract

The study was done to ascertain variations in haematological indices of malaria patients living with HIV in umuahia. A total of 106 subjects were recruited for the study. 80 subjects were HIV positive patients and 26 subjects were malaria-HIV co infected patients.60 subjects were females and 46 were males. All the subjects were selected from the two hospitals. Two different HIV screening kits were used (determine and Unigold test kits) and malaria diagnosed using stained thick films.Haemoglobin was estimated using cynmethaemoglobin method, PCV done using microhaematocrit method and thin film used for differential count. The study showed significant decrease (P<0.05) in platelets and packed cell volume of the HIV-malaria co infected subjects compared to persons living with HIV, significant increase (P<0.05) in total white blood cell and absolute lymphocytes and no significant difference (P<0.05) in absolute neutrophil, haemoglobin and red blood cell of HIV-malaria co infected subjects compared to HIV monoinfection and had a lesser suppression on the absolute lymphocyte. The result also showed significant decrease (P<0.05) in platelets, WBC, significant increase (P<0.05) in PCV and haemoglobin and no significant difference (P>0.05) in lymphocyte, neutrophil and red blood cell of females compared to male of the HIV-malaria co infected subjects. The study showed serious significant difference in most of the haematological parameters studied in the HIV-malaria co infected subjects.

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