Haemodialysis in Severe Barbiturate Poisoning

Lee, H. A.; Ames, A. C.

doi:10.1136/bmj.1.5444.1217

Cited by 58 publications

(12 citation statements)

References 21 publications

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“…Gastric aspiration and lavage does have risks, but we feel that these are often overemphasized-for instance, we have never observed cardiac arrest as a result of the procedure (Lee and Ames, 1965). Perforation of the oesophagus has occurred once in our experience in the last two years : this patient was an elderly chronic alcoholic who was drunk and had been poisoned by barbiturate.…”

Section: Discussionmentioning

confidence: 81%

Gastric aspiration and lavage in acute poisoning.

Matthew¹,

Mackintosh²,

Tompsett³

et al. 1966

BMJ

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1333hospital is £5 2s. 8d., which is a little more than a 14-day course of ampicillin in the dosage used in this trial.It would seem, then, that in ampicillin the physician has a useful addition to his armamentarium for the treatment of pneumonia. SummaryA controlled trial was carried out to compare the use of ampicillin with a combination of penicillin and streptomycin in the treatment of pneumonia. Seventy-eight patients were allocated to the ampicillin group, in which the regime was oral ampicillin 250 mg. six-hourly for 7 or 14 days. Sixtyseven were allocated to the penicillin/streptomycin group, in which the regime required injections of penicillin 1 mega unit b.d. for 7 or 14 days with streptomycin 1 g. b.d. for the first seven days. The treatment groups were comparable, and the results of treatment were similar in the two groups. The only difference of statistical significance was that a larger proportion of cases infected with pneumococci alone became afebrile within one week when treated with ampicillin than when treated with penicillin and streptomycin. Ampicillin appears to be at least as effective as penicillin and streptomycin even in the comparatively small doses used in this trial. There would appear to be an advantage in domiciliary practice in using a drug that can be given by mouth, and if an allowance is made for the cost of giving injections there is little difference in the expense.Our thanks are due to the following doctors who played a major part in the day-to-day conduct of the trial: Drs.

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Section: Discussionmentioning

confidence: 81%

Gastric aspiration and lavage in acute poisoning.

Matthew¹,

Mackintosh²,

Tompsett³

et al. 1966

BMJ

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“…Three of these patients (11%) developed gastric haemorrhage during lavage as a result of which the procedure had to be abandoned. Further complications that have been reported include damage to the stomach (British Medical Journal, 1964), perforation of the oesophagus (Matthew et al, 1966), and cardiac arrest (Lee and Ames, 1965). The psychological sequelae of stomach lavage have not been adequately studied but they may be as important as the physical consequences.…”

Section: Resultsmentioning

confidence: 99%

“…In unconscious patients ipecac syrup is contraindicated. There is considerable support for the opinion that gastric lavage also is contraindicated in comatose patients (Harstad et al, 1942; Journal of the American Medical Association, 1947;Nilsson, 1951;Clemmesen and Nilsson, 1961;Allan, 1961;Arena, 1963;Myschetzky, 1964;Lee and Ames, 1965;Jacobziner, 1966). The place for gastric lavage in paediatric poisoning is extremely uncertain.…”

Section: Resultsmentioning

confidence: 99%

Treatment of the Poisoned Child

Reid¹

1970

Archives of Disease in Childhood

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“…A typical indication for rewarming with haemofiltration or dialysis is an intoxicated and hypothermic patient. If the toxin can be dialysed, simultaneous rewarming of the patient is possible [71] .…”

Section: Extracorporeal Warming Extracorporeal Warming Without Haemodmentioning

confidence: 99%

Diagnosis, prevention and treatment of accidental and perioperative hypothermia

Brandt¹,

Mühlsteff

Imhoff³

2012

Biomedizinische Technik/Biomedical Engineering

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Accidental hypothermia and its variant, perioperative hypothermia, is a rather common clinical phenomenon in patients. This is surprising because the negative effects on clinical outcomes are well described and effective patient-warming devices are available today. The aim of this paper is to describe the physiologic background of accidental and perioperative hypothermia, the clinical relevance and existing prophylaxis and treatment options. Patient warming techniques will be discussed in detail. Remaining technical and clinical challenges and the need for further research will be addressed. We will present existing guidelines and standards and analyse the impact of accidental and perioperative hypothermia on cost effectiveness.

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Haemodialysis in Severe Barbiturate Poisoning

Cited by 58 publications

References 21 publications

Gastric aspiration and lavage in acute poisoning.

Gastric aspiration and lavage in acute poisoning.

Treatment of the Poisoned Child

Diagnosis, prevention and treatment of accidental and perioperative hypothermia

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