Haemoglobin Variants in North Indian Populations

Chahal, S.M.S.; Bansal, Rupinder

doi:10.1080/09720073.2005.11890875

Cited by 3 publications

(4 citation statements)

References 1 publication

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“…Tebal tipisnya pita protein terlihat pada sampel eritrosit burung merpati hias yang memiliki protein utama berupa hemoglobin. Protein hemoglobin memiliki berat molekul 63-66 kDa [16]. Berdasarkan berat molekul protein hemoglobin tersebut, pada jenis burung merpati hias yang terekspresi adalah pada jenis American Fantail dan Indian Fantail dengan berat molekul 65,6 kDa.…”

Section: Pembahasanunclassified

Kekerabatan merpati hias (Columba livia) dilihat dari profil protein darah

Harmoko

Lestari

2022

Livest. Anim. Res.

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Tujuan penelitian ini adalah memprediksi kekerabatan burung merpati hias berdasarkan protein darah. Metode: Metode penelitian yang digunakan, yaitu: deskriptif eksploratif dengan pendekatan berbasis observasi laboratorik. Prosedur Penelitian meliputi: Pengambilan Sampel Darah, Isolasi Protein Darah, Purifikasi, Pengukuran konsentrasi dengan nanodrop spektrofotometer dan Elektroforesis. Analisis Data meliputi: Profil Pita Protein dan Penentuan Berat Molekul Protein dengan rumus RF dan Hubungan Kekerabatan dengan program MVSP versi 3.22.Hasil: Profil protein pada plasma dari merpati hias memperlihatkan perbedaan antara satu jenis merpati hias dengan yang lainnya. Sebagian protein muncul di jenis merpati hias namun tidak muncul di jenis yang lain. Begitu juga dengan protein target yang akan di analisis, ada yang terekspresi dan ada juga yang tidak terekspresi pada jenis merpati hias. Berdasarkan hasil analisis profil protein dan dendogram dari keempat protein spesifik (hemoglobin, transferrin, post transferrin dan immunoglobulin) yang terdapat di dalam eritrosit dan plasma darah, maka dapat dilihat adanya dua kluster. Kluster 1 ditempati oleh varietas merpati hias Moven dan kluster 2 ditempati oleh varietas merpati hias Lahore,

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Section: Pembahasanunclassified

Kekerabatan merpati hias (Columba livia) dilihat dari profil protein darah

Harmoko

Lestari

2022

Livest. Anim. Res.

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“…Haemoglobin (Hb), the red respiratory protein found in mammalian erythrocytes is one of the most informative molecules in primate blood [1]. In adult humans, the most common haemoglobin type is a tetramer known as haemoglobin-A consists of four separate polypeptide chains of amino acids and each subunit is composed of a protein chain tightly associated with a non-protein haeme group that fix oxygen.…”

Section: Introductionmentioning

confidence: 99%

“…Haemoglobin variants are a part of the normal embryonic and fetal development which can also be pathologic mutant forms caused by variations in genetics of haemoglobin in a population. Haemoglobinopathies covers a group of hereditary disorders in which the structure (qualitative change) or the rate of synthesis (quantitative change) of one of the normal haemoglobin chain is altered [1]. Haemoglobinopathies causes varying degrees of microcytic anemia that can range from insignificant to life threatening [2].…”

Section: Introductionmentioning

confidence: 99%

Haemoglobin Variants among the Bengali Muslims and the Meiteis in two Villages of Cachar District of Assam, India

2016

International Journal of Research in Sociology and Anthropology

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“…The structure of haemoglobin variants is similar to normal haemoglobin (HbA) except there is alteration in the sequence of amino acids usually in the β-chain. Haemoglobinopathies can be divided into two groups -the structural haemoglobin variants due to single point mutation in the globin structure (like HbS , C, D, and E) and the thalassemia, where the rate of synthesis of globin chain is inefficient [1] . The clinical spectrums of the disorders vary from asymptomatic conditions to serious disorders like death in utero.…”

Section: Introductionmentioning

confidence: 99%