Half‐sandwich ruthenium complexes with <scp>S</scp>chiff base ligands bearing a hydroxyl group: Preparation, characterization and catalytic activities

Jia, Wenhua; Wang, Zhi‐Bao; Zhi, Xue-Ting

doi:10.1002/aoc.5289

Cited by 11 publications

(3 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…62–64 Complexes Ru1 and Ru2 were prepared in high yields by modifying a reported procedure. 65,66 Their typical synthesis involves the reactions between [Ru( p -cymene)(μ-Cl)Cl] 2 and salicylaldimine H 2 L 1 or HL 2 in the presence of potassium carbonate as a base in ethanol at room temperature (Scheme 3). Crude products precipitate out as dark red solids which were recrystallized from the dichloromethane : ethanol (4 : 1 v/v) mixture.…”

Section: Resultsmentioning

confidence: 99%

A highly active and chemoselective homobimetallic ruthenium catalyst for one-pot reductive amination in water

Deshmukh,

Rana,

Yadav

et al. 2024

Green Chem.

View full text Add to dashboard Cite

Two new Ru(II) compounds, bimetallic [(p-cymene)2(RuCl)2L1] (Ru1) and monometallic [(p-cymene)(RuCl)L2] (Ru2) (where L1=2,2'-((1E,1'E)-((3,3',5,5'-tetraisopropyl-[1,1'-biphenyl]-4,4'diyl)bis(azaneylylidene))bis(methaneylylidene)) diphenoxide) and L2=(2,6-diiso-propylphenyl)imino)methyl)phenoxide) incorporating Schiff base ligands have been synthesised and characterised by various spectroscopic and analytical...

show abstract

Section: Resultsmentioning

confidence: 99%

A highly active and chemoselective homobimetallic ruthenium catalyst for one-pot reductive amination in water

Deshmukh,

Rana,

Yadav

et al. 2024

Green Chem.

View full text Add to dashboard Cite

show abstract

“…Naphthaldehyde-based compounds have numerous applications such as electrochemical, catalytic, photoluminescence, analytical, cytotoxic, antimicrobial, and in vitro anticancer, antiproliferative, antioxidant, and other applications. [34][35][36][37][38][39][40][41][42] Transition metal compounds play important role in bio-inorganic chemistry and redox enzyme systems. [43] In addition, transition metal complexes have played a significant role in the development of metal-based anticancer agents.…”

Section: Introductionmentioning

confidence: 99%

Co (II), Ni (II), and Cu (II) complexes of 4,6‐bis(2‐hydroxynaphthalen‐1‐yl)methyl‐ene)hydrazono)ethyl)benzene‐1,3‐diol: Synthesis, spectroscopic, biological, and theoretical studies

Samy

2022

Applied Organom Chemis

View full text Add to dashboard Cite

A new hydrazone ligand 4,6‐bis(2‐hydroxynaphthalen‐1‐yl)methyl‐ene)hydrazono)ethyl)benzene‐1,3‐diol (H4L; DHNAPH) was synthesized by the reaction of 4,6‐bis(1‐hydrazonoethyl)benzene‐1,3‐diol (NH2DAR) with 2‐hydroxy 1‐naphthaldehyde. Co (II), Ni (II), and Cu (II) complexes ([M2L(H2O)6].nH2O.mEtOH (M = Co, Ni or Cu; n = 0.5 or 1; and m = 0.5 or 0) of DHNAPH have been successfully synthesized. Characterization of DHNAPH and its complexes was performed by analytical, spectral (infrared [IR], mass, UV–Vis, 1H NMR, and electron spin resonance [ESR]), powder X‐ray diffraction (XRD), magnetic susceptibility, molar conductivity, and thermal gravimetric analysis (TGA) techniques. The analytical data, magnetic moments, and spectral studies recognized octahedral geometries for DHNAPH complexes. DHNAPH acts as a bis (dibasic tridentate) via (C=N azomethine and 2 OH) with metal in complexes. The XRD patterns for DHNAPH and its complexes indicate crystalline nature of DHNAPH and its Cu complex. DHNAPH has triclinic system, while copper‐DHNAPH has a tetragonal system with different unit cell parameters. Theoretical studies showed that there is a good relation between experimental IR data and theoretical calculation. The activity of DHNAPH and its complexes against Hepatocellular carcinoma, fungi, and bacteria has been tested. The new complexes are more active than DHNAPH, and the highest antitumor activity was given by copper (II) complex, which showed lower IC50 than that of Cisplatin. The DNA binding of DHNAPH and Cu‐DHNAPH has been investigated. Molecular docking studies showed that all the tested compounds show good binding scores revealing good fitting in between the DNA strands. There is an agreement between docking data and DNA binding results.

show abstract

“…Naphthaldehyde-based compounds have numerous presentations such as electrochemical, catalytic, photoluminescence, analytical, cytotoxic, antimicrobial and in vitro anticancer, antiproliferative, antioxidant, catechol's studies [33][34][35][36][37][38][39][40][41][42][43] Transition metal compounds play important role in bio-inorganic chemistry and redox enzyme systems [44]. Copper is one of the most important elements in the human body.…”

Section: Introductionmentioning

confidence: 99%

Binuclear Co(II), Ni(II) and Cu(II) Complexes of a new Bis(tridentate) Hydrazone Ligand: Synthesis, Thermal, Spectroscopic, Biological, Molecular Docking and Theoretical Studies

Samy

2021

Preprint

View full text Add to dashboard Cite

A new hydrazone ligand; 4,6-bis(2-hydroxynaphthalen-1-yl)methyl-ene)hydrazono)ethyl)benzene-1,3-diol (H4L; DHNAPH) was synthesized by the reaction of 4,6-bis(1-hydrazonoethyl)benzene-1,3-diol (NH2DAR) with 2-hydroxy 1-naphthaldehyde. Co(II), Ni(II) and Cu(II)- complexes ([M2L(H2O)6].nH2O.mEtOH; M = Co, Ni or Cu, n = 0.5 or 1 and m = 0.5 or 0) of DHNAPH have been successfully synthesized. Characterization of DHNAPH and its complexes was performed by analytical, spectral (IR, mass, UV-Vis, 1H NMR and ESR), magnetic susceptibility, molar conductivity and thermal gravimetric analysis (TGA) techniques. The scanning electron microscopy (SEM) was used for detection of the morphology of DHNAPH and its Co- and Ni-complexes, which refers that the DHNAPH complexes are in the nano scale. The analytical data, magnetic moments and spectral studies recognized octahedral geometries for DHNAPH complexes. DHNAPH acts as a bis(dibasic triadentate) via (C=Nazomethine and 2 OH) with metal in complexes. The optimized structure of DHNAPH and its complexes has been done theoretically by Hyperchem program and structural parameters were linked with the IR experimental data. The activity of DHNAPH and its complexes against Hepatocellular carcinoma, fungi and bacteria has been tested. The new complexes are more active than DHNAPH and the highest antitumor activity was given by copper(II) complex. The DNA-binding of DHNAPH and Cu- DHNAPH has been investigated. Molecular docking studies showed that all the tested compounds show good binding score revealing good fitting in between the DNA strands. There is agreement between docking data and DNA binding results.

show abstract

Half‐sandwich ruthenium complexes with Schiff base ligands bearing a hydroxyl group: Preparation, characterization and catalytic activities

Cited by 11 publications

References 56 publications

A highly active and chemoselective homobimetallic ruthenium catalyst for one-pot reductive amination in water

A highly active and chemoselective homobimetallic ruthenium catalyst for one-pot reductive amination in water

Co (II), Ni (II), and Cu (II) complexes of 4,6‐bis(2‐hydroxynaphthalen‐1‐yl)methyl‐ene)hydrazono)ethyl)benzene‐1,3‐diol: Synthesis, spectroscopic, biological, and theoretical studies

Binuclear Co(II), Ni(II) and Cu(II) Complexes of a new Bis(tridentate) Hydrazone Ligand: Synthesis, Thermal, Spectroscopic, Biological, Molecular Docking and Theoretical Studies

Contact Info

Product

Resources

About