C harles Bonnet syndrome (CBS) is a rare medical disorder that is characterized by vivid, complex, and recurrent visual hallucinations that occur in visually impaired patients in the absence of neurological or psychiatric diagnoses. It is a clinical diagnosis of exclusion, and no standard treatment is presently available. In this case report, we present a 69-year-old male patient with CBS and a history of legal blindness in both eyes, who responded to a trial of olanzapine.
CASEA 69-year-old White male nursing home resident presents with visual hallucinations of 5 months' duration that occur during the daytime and both before and after sleep. No specific trigger was identified for the visual hallucinations. The patient describes the hallucinations as clear and detailed and states he initially was not aware, but as time passed, he has full insight and awareness of them. The hallucinations occurred once per month for the first 3 months but have increased in frequency to multiple times in a day within the last 2 months. He described the most recent one (2 days ago) in which he was involved in a fight with an unknown man who stabbed him in the chest and made him suffer a fall. He stated that his hallucinations were mostly about people hurting him and stated that it lasts for a while until he gets attacked. He also reports daytime feelings of paranoia, that is, someone is going to hurt him from the back, midnight awakenings associated with feelings of anxiety, and an inability to resume sleep since the onset of the hallucinations.The patient denied of having any unilateral distribution, or associated headache, or frightening content of hallucinations. Simple patterns, spots, shapes, or line, or associated confabulation of vision are also absent. The patient also denied of having abnormal visual perceptions such as macropsia, micropsia, or metamorphopsia. The patient denied all other types of hallucinations, delusions, suicidal or homicidal ideations, as well as headache, trauma, and fever. Before today's visit, he had seen an outpatient psychiatrist for visual hallucinations and sleep difficulties (4 and 6 months ago). The patient was initially started on loxapine 5 mg 6 months ago, which was