Halogenated and parent polycyclic aromatic hydrocarbons in vegetables: Levels, dietary intakes, and health risk assessments

Wang, Li; Li, Chunmei; Jiao, Bining; Li, Qiwan; Su, Hang; Wang, Jing; Jin, Fen

doi:10.1016/j.scitotenv.2017.10.336

Cited by 57 publications

(19 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moukas et al 30 measured polybrominated diphenyl ethers and brominated diphenyl ether (BDE) using LC-APPI-MS/MS. Diphenyl ethers with four to six bromine atoms were ionized in 31 The present results are consistent with the report by Ohura et al 1 that certain BrPAHs can be photodegraded and debrominated. The ion transitions of the BrPAHs were similar between GC-MS/MS and LC-DA-APPI-MS/MS.…”

Section: Resultssupporting

confidence: 92%

Quantification of Brominated Polycyclic Aromatic Hydrocarbons in Environmental Samples by Liquid Chromatography Tandem Mass Spectrometry with Atmospheric Pressure Photoionization and Post-column Infusion of Dopant

et al. 2020

View full text Add to dashboard Cite

A sensitive method for the quantification of brominated polycyclic aromatic hydrocarbons (BrPAHs) in environmental samples is yet to be developed. Here, we optimized the analytical conditions for liquid chromatography tandem mass spectrometry with atmospheric pressure photoionization and post-column infusion of dopant (LC-DA-APPI-MS/MS). We then compared the sensitivity of our developed method with that of conventional gas chromatography high-resolution MS (GC-HRMS) by comparing the limits of quantification (LOQs) for a range of BrPAHs. Finally, to evaluate our developed method, 12 BrPAHs in sediments and fish collected from Tokyo Bay, Japan, were analyzed; 9 common PAHs were also targeted. The LOQs of the developed analytical method were 14-160 times lower than those of GC-HRMS for the targeted BrPAHs. The developed analytical method is a sensitive approach for determining the concentrations of BrPAHs in sediment and fish samples.

show abstract

Section: Resultssupporting

confidence: 92%

Quantification of Brominated Polycyclic Aromatic Hydrocarbons in Environmental Samples by Liquid Chromatography Tandem Mass Spectrometry with Atmospheric Pressure Photoionization and Post-column Infusion of Dopant

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Little has become known about the whole EU 15 + 1 PAHs in liquid milk samples. In addition, some PAH derivatives, such as chlorinated PAHs (ClPAHs) and oxygenated PAHs (OPAHs), have attracted attention due to their more toxic effects than their parent PAHs. − To solve this problem, there is a need to develop a robust PAH detection method and to conduct an extensive investigation of dairy products.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Typical Chlorinated, Oxygenated, and European Union Priority Polycyclic Aromatic Hydrocarbons in Milk Samples and Milk Powders

Yan

Gong

et al. 2021

J. Agric. Food Chem.

View full text Add to dashboard Cite

An increasing number of studies have suggested that PAH contamination in dairy products demands high concern. This study established an efficient determination method for the European Union 15 + 1 PAHs and four PAH derivatives in dairy samples using a QuEChERS method coupled with GC-QqQ-MS. The optimized method obtained a recovery of 63.38−109.17% with a precision of 3.82−15.62%, and the limit of detection and limit of quantification were 0.08−0.78 and 0.27−2.59 μg/kg, respectively. The validated method was then successfully applied to identify the 20 PAHs in 82 dairy samples, including 43 commercial milk samples and 39 milk powders. The total PAH concentrations ranged from 2.37 to 11.83 μg/kg, and benzo[a]pyrene was only quantified in one milk and one milk powder sample at 0.35 and 0.42 μg/kg, respectively. The concentrations of PAH4 in milk samples and milk powders were not quantified (nq)−3.99 and nq−4.51 μg/kg, respectively. The results confirmed the appreciable occurrence of PAHs in dairy products, especially in infant formula. The data in this study provide a scientific basis for assessment on origin tracing, dietary exposure, and health risk of PAHs and their derivatives.

show abstract

“…Polycyclic aromatic hydrocarbons (PAHs) are a group of widespread environmental pollutants, primarily derived from incomplete combustion of fossil fuels and biomass [1]. Compared with natural exposure sources, industrial production processes, motor vehicle exhaust, cigarette smoking and residential fuel combustion are the main emission sources of PAHs in the human living environment [2].…”

Section: Introductionmentioning

confidence: 99%

Oxidative damage mediates the association between polycyclic aromatic hydrocarbon exposure and lung function

Cao

Zhou

Tan³

et al. 2020

Environ Health

View full text Add to dashboard Cite

Background: Exposure to polycyclic aromatic hydrocarbons (PAHs) is related to decreased lung function. However, whether oxidative damage is involved in this relationship remains unclear. This study was aimed to explore the potential mediating role of oxidative DNA or lipid damage in the association between PAH exposure and lung function. Methods: The urinary levels of monohydroxy polycyclic aromatic hydrocarbon metabolites (OH-PAHs) and lung function parameters were measured among 3367 participants from the baseline of the Wuhan-Zhuhai cohort. Urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) and 8-isoprostane (8-iso-PGF2α) were determined to evaluate the individuals' oxidative DNA and lipid damage degrees, respectively. Linear mixed models were used to investigate the associations of urinary OH-PAHs, 8-OHdG and 8-iso-PGF2α with lung function parameters. Mediation analysis was further conducted to assess the potential role of oxidative damage in the association between urinary OH-PAHs and lung function. Results: Each one-percentage increase in the sum of urinary OH-PAHs, high-molecular-weight or low-molecular-weight OH-PAHs (ƩOH-PAHs, ƩHMW OH-PAH or ƩLMW OH-PAHs, respectively) was associated with a 0.2152-, 0.2076-or 0.1985ml decrease in FEV 1 , and a 0.1891-, 0.2195-or 0.1634-ml decrease in FVC, respectively. Additionally, significantly positive dose-response relationships of ƩOH-PAHs, ƩHMW OH-PAH and ƩLMW OH-PAHs with urinary 8-OHdG or 8-iso-PGF2α, as well as an inverse dose-response relationship between urinary 8-OHdG and FVC, were observed (all P for trend < 0.05). Mediation analysis indicated that urinary 8-OHdG mediated 14.22% of the association between ƩHMW OH-PAH and FVC. Conclusion: Higher levels of oxidative DNA damage might be involved in the decreased levels of FVC caused by highmolecular-weight PAH exposure.

show abstract

Halogenated and parent polycyclic aromatic hydrocarbons in vegetables: Levels, dietary intakes, and health risk assessments

Cited by 57 publications

References 52 publications

Quantification of Brominated Polycyclic Aromatic Hydrocarbons in Environmental Samples by Liquid Chromatography Tandem Mass Spectrometry with Atmospheric Pressure Photoionization and Post-column Infusion of Dopant

Quantification of Brominated Polycyclic Aromatic Hydrocarbons in Environmental Samples by Liquid Chromatography Tandem Mass Spectrometry with Atmospheric Pressure Photoionization and Post-column Infusion of Dopant

Simultaneous Determination of Typical Chlorinated, Oxygenated, and European Union Priority Polycyclic Aromatic Hydrocarbons in Milk Samples and Milk Powders

Oxidative damage mediates the association between polycyclic aromatic hydrocarbon exposure and lung function

Contact Info

Product

Resources

About