Halothane Inhibition of Propranolol Metabolism is Stereoselective

Editorial

“…Although most of their properties are identical, the R and S enantiomers may form different three-dimensional relationships in the asymmetric environment of receptors and enzymes; this may result in significant differences in. their pharmacodynamic effects and their pharmacokinetic properties [3,4]. These differences in biological activity are not surprising, since the individual enantiomers combine with receptors or enzymes consisting of chiral amino-acids (i.e.…”