Hamartome splénique, thrombopénie sévère et macrocrânie chez un nouveau-né

Radouani, Mohammed Amine; Azzaoui, S.; Mammad, C.; Knouni, Houria; Chefchaouni, K.; Benchekroun, I.; Barkat, Amina

doi:10.1016/j.arcped.2015.09.016

Cited by 1 publication

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…All the cases analyzed in this review were diagnosed with SH by histopathological examination. A report by Raouani et al [ 34 ] was excluded due to a lack of histopathological confirmation of the diagnosis of SH. Data on all included cases found in the literature (46 patients), as well as on our case, are listed in .…”

Section: Literature Searchmentioning

confidence: 99%

Splenic hamartomas in children

Milickovic,

Rasic,

Cvejic

et al. 2024

World J Clin Cases

View full text Add to dashboard Cite

Splenic hamartomas (SHs) are uncommon, benign vascular lesions of unclear etiology and are mostly found incidentally on abdominal images, at surgery, or at autopsy. Since the first case description, in 1861, less than 50 pediatric SH cases have been reported in the literature. In this article, we have performed an analysis of all SH cases in children published in the literature to date and presented our case of an 8-year-old male with SH. These lesions in children were shown to cause symptoms more often than in the adult population. The observed SH sizes in children ranged from a few millimeters to 18 cm, and the symptomatic lesions were mostly larger or multiple. The most common clinical finding was splenomegaly. Signs of hypersplenism were present in children with a single SH larger than 4.5 cm (diameter range: 4.5-18.0 cm) and in those with multiple hamartomas, ranging from a few millimeters to 5 cm. Eighty percent of patients with available laboratory findings had hematological abnormalities such as anemia, thrombocytopenia, or pancytopenia. Other symptoms and signs included abdominal pain, recurrent infections, fever, night sweats, lethargy, growth retardation, and weight loss. The use of multiple imaging modalities may suggest the preoperative diagnosis of a splenic mass in children and determine the therapeutic approach. However, the final diagnosis of SH relies on histopathological evaluation. Surgery, including total or partial splenectomy (PS), is the mainstay of SH management. Although total splenectomy carries a greater risk of overwhelming post-splenectomy infection than PS it has remained the most performed surgical procedure in children with SH. In the majority of pediatric patients with symptomatic SH, resolution of symptoms and resolution or improvement of cytopenias occurred after surgical treatment.

show abstract

Section: Literature Searchmentioning

confidence: 99%