HAMP quality assurance protocol of hyperthermia systems

Triantopoulou, Sotiria; Antypas, C.; Karaiskos, P.; Armpilia, Christina; Platoni, Kalliopi; Kouloulias, Vasileios

doi:10.1016/j.ejmp.2016.07.516

Cited by 1 publication

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“…Avid HT practitioners argue that the reasons for the hindered progress in this field are not the lack of efficacy, but the lack of funding, limited access, poorer tolerance of older technology, lack of quality assurance processes, poor temperature monitoring and heterogenous practices [1,6,10,11].To advance the field, international groups such as the European Society of Hyperthermic Oncology (ESHO) and Society of Thermal Medicine (STM) have been formed, with the aim of promoting scientific knowledge and facilitating cooperative research. Quality assurance guidance [12][13][14][15] has also been published this past decade, to provide technical standardisations for the clinical applications of RHT. These serve to ensure the appropriate use of Regional Hyperthermia (RHT) and establish treatment standards to improve clinical outcomes.…”

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confidence: 99%

A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers

Chia

Tan

et al. 2023

Cancers

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Regional hyperthermia therapy (RHT) is a treatment that applies moderate heat to tumours in an attempt to potentiate the effects of oncological treatments and improve responses. Although it has been used for many years, the mechanisms of action are not fully understood. Heterogenous practices, poor quality assurance, conflicting clinical evidence and lack of familiarity have hindered its use. Despite this, several centres recognise its potential and have adopted it in their standard treatment protocols. In recent times, significant technical improvements have been made and there is an increasing pool of evidence that could revolutionise its use. Our narrative review aims to summarise the recently published prospective trial evidence and present the clinical effects of RHT when added to standard cancer treatments. In total, 31 studies with higher-quality evidence across various subsites are discussed herein. Although not all of these studies are level 1 evidence, benefits of moderate RHT in improving local tumour control, survival outcomes and quality of life scores were observed across the different cancer subsites with minimal increase in toxicities. This paper may serve as a reference when considering this technique for specific indications.

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