Hand grip strength in patients with chronic obstructive pulmonary disease

Abstract

PurposeHand grip strength (HGS) is a simple way of predicting the risk of cardiovascular disease and all-cause mortality in the general population. However, the practical significance of grip strength in patients with COPD is uncertain. The aim of this study was to compare HGS between subjects with and without COPD and to evaluate its clinical relevance in patients with COPD by using a national survey.MethodsData were collected from the Korean National Health and Nutrition Examination Survey. The study included 421 adults with COPD and 2,542 controls who completed questionnaires, spirometry, and a HGS test. HGS was compared between subjects with and without COPD, and the association between grip strength, lung function, and quality of life (QoL) was evaluated.ResultsThe mean HGS was 33.3±9.1 kg in the COPD group and 29.9±9.5 kg in the non-COPD group; adjusted HGS was 30.9±0.33 kg and 30.9±0.11 kg, respectively (P=0.99). HGS was not related to forced vital capacity (β=0.04, P=0.70) or forced expiratory volume in 1 second (β=0.11, P=0.24) in multivariable analysis. HGS was independently associated with the EQ-5D index, but the relationship was stronger in the COPD group (β=0.30, P<0.001) than in the non-COPD group (β=0.21, P<0.001). The results were similar for each component of the EQ-5D, including mobility (β=−0.25, P<0.001), daily activity (β=−0.19, P=0.01), pain/discomfort (β=−0.32, P<0.001), and anxiety/depression (β=−0.16, P=0.01).ConclusionHGS was not different between subjects with and without COPD, but was associated with QoL – including mobility, daily activity, pain/discomfort, and anxiety/depression – in patients with COPD. The HGS test could be used as a marker of QoL in patients with COPD and could assist risk stratification in clinical practice.

Better pulmonary function is associated with increased handgrip strength in a healthy Chinese Han population

“…Higher HGS is associated with a range of health outcomes [24]. Some studies have supported that HGS might be an additional method for evaluating the quality of life in COPD patients [8,11]. Our results support the hypothesis that HGS can be used as an auxiliary evaluation index for lung function, but whether it can be a predictor for ageing-related pulmonary disease still needs further studies.…”

“…Most studies on the correlation between pulmonary function and HGS have focused on small samples of individuals with pulmonary disease, stroke, diabetes or other diseases [7][8][9][10][11][12]. Less attention has been paid to analyse the association between HGS and pulmonary function among the healthy Chinese Han population.…”

Factors Associated With Poor Sleep in Older Women Diagnosed With Breast Cancer

“…Functional domain: Sleep disorders and poor sleep are associated with impaired functional status (Loh et al, 2017;Song, Dzierzewski, et al, 2015), poor gait, lack of confidence in balance (Tyagi, Perera, & Brach, 2017), and poor grip strength (Jeong et al, 2017). Sleep disorders affect muscle mass and functioning, which can translate into poor physical performance (Auyeung et al, 2015).…”

SR stress in locomotor muscles of patients with chronic obstructive pulmonary disease

“…The reduction in HGS was more prominent in participants with COPD-3 & 4 (≈19.5%, p < 0.05) than participants with COPD-1 & 2 (≈7.7%, p < 0.05), when compared to control group. The association of serum biomarkers with HGS in COPD has been reported before (30). Here, we investigated the serum association of serum AGP and TSA with HGS in healthy controls and COPD participants.…”