Hand‐held pulsed photothermal radiometry system to estimate epidermal temperature rise during laser therapy

Jung, Byungjo; Kim, Chang-Seok; Choi, Bernard; Nelson, J. Stuart

doi:10.1111/j.0909-752x.2006.00175.x

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…This non-contact technique is known as pulsed photo-thermal radiometry (PPTR) and has been previously suggested as a diagnostic tool to enhance safety and efficacy [11,12]. Criteria for clinically acceptable skin injury were defined as those commonly observed after LHR.…”

Section: Introductionmentioning

confidence: 99%

Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)

et al. 2007

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Section: Introductionmentioning

confidence: 99%

Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)

et al. 2007

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“…Pulsed photothermal radiometry (PPTR) is a non-contact optical method that applies a pulsed laser to generate heat due to optical absorption and measures thermal diffusivity based on heat propagation through the material 21 . This method has been recently used for physiologic characterization of skin 24 and to predict temperature rise in patients undergoing laser therapy 25 . Both of these techniques apply stimulus over a large area and the subsequent thermal response becomes blurred due to thermal conductivity, significantly reducing the spatial resolution.…”

Section: Discussionmentioning

confidence: 99%

Focal dynamic thermal imaging for label-free high-resolution characterization of materials and tissue heterogeneity

O’Brien

Meng

Shmuylovich

et al. 2020

Sci Rep

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Evolution from static to dynamic label-free thermal imaging has improved bulk tissue characterization, but fails to capture subtle thermal properties in heterogeneous systems. Here, we report a label-free, high speed, and high-resolution platform technology, focal dynamic thermal imaging (FDTI), for delineating material patterns and tissue heterogeneity. Stimulation of focal regions of thermally responsive systems with a narrow beam, low power, and low cost 405 nm laser perturbs the thermal equilibrium. Capturing the dynamic response of 3D printed phantoms, ex vivo biological tissue, and in vivo mouse and rat models of cancer with a thermal camera reveals material heterogeneity and delineates diseased from healthy tissue. The intuitive and non-contact FDTI method allows for rapid interrogation of suspicious lesions and longitudinal changes in tissue heterogeneity with high-resolution and large field of view. Portable FDTI holds promise as a clinical tool for capturing subtle differences in heterogeneity between malignant, benign, and inflamed tissue.

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“…To obtain an optimal thermal e®ect in thermal therapy, the temperature inside the skin tissue and skin surface should be accurately controlled. 9,10 Many methods are available for measuring the temperature in the tissue phantom. The most e®ective method is temperature measurement using ultrasound waves or high-resolution thermal-imaging camera.…”

Section: Introductionmentioning

confidence: 99%

Near-infrared laser irradiation of a multilayer agar-gel tissue phantom to induce thermal effect of traditional moxibustion

Cho

Prasad

Kim

2018

J. Innov. Opt. Health Sci.

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Traditional moxibustion therapy can stimulate heat and blood-vessel expansion and advance blood circulation. In the present study, a novel noncontact-type thermal therapeutic system was developed using a near-infrared laser diode. The device allows direct interaction of infrared laser light with the skin, thereby facilitating a controlled temperature distribution on the skin and the deep tissues below the skin. While using a tissue-mimicking phantom as a substitute for real skin, the most important optical and thermal parameters are the absorption/attenuation coefficient, thermal conductivity, and specific heat. We found that these parameters can be manipulated by varying the agar-gel concentration. Hence, a multilayer tissue-mimicking phantom was fabricated using different agar-gel concentrations. Thermal imaging and thermocouples were used to measure the temperature distribution inside the phantom during laser irradiation. The temperature increased with the increase in the agar-gel concentration and reached a maximum value under the tissue phantom surface. To induce a similar thermal effect of moxibustion therapy, controlled laser-irradiation parameters such as output power, wavelength and pulse width were obtained from further analysis of the temperature distribution. From the known optothermal properties of the patient’s skin, the temperature distribution inside the tissue was manipulated by optimizing the laser parameters. This study can contribute to patient-specific thermal therapy in clinics.

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Hand‐held pulsed photothermal radiometry system to estimate epidermal temperature rise during laser therapy

Abstract: A fiber-free, hand-held AC-coupled PPTR system is capable of accurate epidermis temperature rise (DeltaT(epi)) measurements of human skin during pulsed laser exposure.

Cited by 4 publications

References 12 publications

Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)

Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)

Focal dynamic thermal imaging for label-free high-resolution characterization of materials and tissue heterogeneity

Near-infrared laser irradiation of a multilayer agar-gel tissue phantom to induce thermal effect of traditional moxibustion

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