Hand hygiene for the prevention of infections in neonates

Kuti, Bankole Peter; Ogunlesi, TA; Oduwole, Olabisi; Oringanje, Chukwudi; Udoh, Ekong; Meremikwu, Martin

doi:10.1002/14651858.cd013326

Cited by 8 publications

(6 citation statements)

References 26 publications

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“…In the community, the risk of NS is determined by poor hygiene in general (of the hands, bottle-feeding and poor umbilical cord care practices) [33,35,36].…”

Section: Risk Factors For Lonsmentioning

confidence: 99%

Neonatal sepsis: A review of the literature

Nyenga¹,

Mukuku²,

Wembonyama³

2021

Theory Clin Pract Pediatr

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Neonatal sepsis contributes significantly to neonatal morbidity and mortality and is a major public health challenge around the world. Depending on the mode of occurrence, a distinction is made between maternal-transmitted infection and that acquired in the postnatal period. Although the etiologies maternally transmitted diseases are well understood, those of postnatal acquired infections are variable depending on the epidemiology of each hospital environment. On the one hand, risk factors for maternal-transmitted infections are maternal sepsis, prolonged premature rupture of membranes, chorioamnionitis, and bacteriuria in the mother during pregnancy. On the other hand, risk factors for postnatal acquired infections are prematurity, low birth weight, lack of hygiene, and invasive therapeutic interventions. The diagnosis is based on a series of anamnestic, clinical and biological features. Although the positive diagnosis is based on the isolation of the germ by culture on a body sample (blood, cerebrospinal fluid, urine, etc.); its low sensitivity leads to the use of markers of the acute phase of inflammation such as C-reactive protein, procalcitonin and interleukins. New molecular biology techniques are promising and offer precise diagnosis with rapid results. Empirical management is a function of microbial ecology while definitive treatment is guided by the results of microbial culture. This article presents the essential elements for understanding neonatal sepsis and discusses new diagnosis and therapeutic management. It offers a thorough reading based on the issue of infections in newborns.

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“…In the community, the risk of NS is determined by poor hygiene in general (of the hands, bottle-feeding and poor umbilical cord care practices) [33,35,36].…”

Section: Risk Factors For Lonsmentioning

confidence: 99%

Neonatal sepsis: A review of the literature

Nyenga¹,

Mukuku²,

Wembonyama³

2021

Theory Clin Pract Pediatr

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“…Prevention and early diagnosis are clearly preparatory for the treatment and condition its timeliness. Prevention is the most effective measure against sepsis, especially the scrupulous hand hygiene of the clinical operators [7]. Early diagnosis of sepsis would allow timely antibiotic therapy, which is essential to reduce the severity and duration of the disease, as well as lead to more favourable outcomes.…”

Section: Introductionmentioning

confidence: 99%

Intelligent Neonatal Sepsis Early Diagnosis System for Very Low Birth Weight Infants

et al. 2021

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Neonatal sepsis is a critical pathology that particularly affects the neonates in intensive care, especially if they are preterm and low birth weight, with an incidence varying between 1and 40% according to the onset (early or late) of the disease. Prompt diagnostic and therapeutic interventions could reduce the high percentage of mortality that characterises this pathology, especially in the premature and low weight neonates. The HeRO score analyses the heart rate variability and represents the risk of contracting sepsis because of the hospitalization in the neonatal intensive care unit up to 24 h before the clinical signs. However, it has been demonstrated that the HeRO score can produce many false-positive cases, thus leading to the start of unnecessary antibiotic therapy. In this work, the authors propose an optimised artificial neural network model able to diagnose sepsis early based on the HeRO score along with a series of parameters strictly connected to the risk of neonatal sepsis. The proposed methodology shows promising results, outperforming the diagnostic accuracy of the only HeRO score and reducing the number of false positives, thus revealing itself to be a promising tool for supporting the clinicians in the daily clinical practice.

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“…Our findings are in agreement to (Blencowe et al 2011) who indicated that maternal handwashing during the postnatal period reduced cord infections, which would translate to a reduction in all-cause neonatal mortality. Multiple literature shows that this inexpensive way of preventing neonatal infections at home and in the hospitals, and that, further reduces related mortalities, is practicable in resource-limited settings such as ours (Daniels et al, 1999;Kuti et al, 2019;WHO, 2009).…”

Section: Predictors Of Omphalitis Among Neonatesmentioning

confidence: 99%

Predictors of Omphalitis among Spontaneous Vertex Delivery Neonates in Nakuru County Hospital, Kenya

Kinanu¹,

Mwaura²,

Karani³

2020

int.jour.sci.res.mana.

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Background; Omphalitis (umbilical cord infection) among new-borns is common and a major cause of neonatal deaths in developing countries. Annually, about 4 million neonatal deaths occur around the world. Of these, >30% are caused by infections that mainly from umbilical cord. Cord care practices may directly contribute neonatal infections, largely contributing tothis was part data from a larger randomized trial among 540 participant’s neonatal deaths. Cord infections are more prevalent in developing countries because of the high rates of poverty and unhygienic practices. Objective: To determine the predictors of omphalitis among neonates in Nakuru County Hospital, Kenya. Methodology This was part data from a larger randomized trial among 540 participants. Findings: The prevalence of Omphalitis was 23.1. Babies whose mothers’ did not wash hands when eating had 2.14 times risk of developing cord infection compared to those babies whose mothers’ indicated otherwise [AOR=2.14; 95%CI=1.28 - 3.57; p=0.004]. Likewise, babies whose mothers’ never folded diapers backwards were twice likely over those who did to develop cord infection [AOR=1.88; 95%CI=1.03 - 3.44; p=0.039]. Babies whose mothers’ stayed in different rooms had 7.35 times risk of developing cord infection [AOR=7.35; 95%CI=3.40 - 15.91; p<0.001] over those roomed in. Conclusion and recommendation: Maternal and caretakers hand hygiene, folding back of diapers and rooming in are critical in cord infection prevention. Health education to mothers and care takers on the importance of hand hygiene, diaper application and importance of rooming in is recommended to minimise omphalitis and consequential morbidity.

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Hand hygiene for the prevention of infections in neonates

Cited by 8 publications

References 26 publications

Neonatal sepsis: A review of the literature

Neonatal sepsis: A review of the literature

Intelligent Neonatal Sepsis Early Diagnosis System for Very Low Birth Weight Infants

Predictors of Omphalitis among Spontaneous Vertex Delivery Neonates in Nakuru County Hospital, Kenya

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