This article unveils MoSIoT (Modeling Scenarios of the Internet of Things), an innovative framework meticulously designed to simulate IoT systems, addressing the nuanced needs of individuals with hearing impairments. Grounded in the quality-of-life framework proposed by Verdugo et al., MoSIoT has been enriched and evolved to integrate and manage a spectrum of deafness technologies, thereby marking a significant enhancement in the overall quality of life for the affected individuals. The focal point of this work is the advocacy for accessibility and well-being through technology-driven and inclusive solutions. The presented case study provides a comprehensive insight into the transformative impact of MoSIoT, highlighting improvements in key quality of life dimensions such as “Interpersonal Relationships”, “Emotional Well-Being”, and “Personal Development”. These enhancements underscore the pivotal role of continuous innovation and inclusive design in the evolution of assistive technologies. The article delves into the intricacies of the system’s implementation, exploring its service-based architecture, which ensures modularity, scalability, and adaptability to diverse user needs and technological advancements. Furthermore, the potential for future research and development in this field is discussed, emphasizing the endless possibilities and avenues for enhancing assistive technology and promoting an inclusive and accessible future for individuals with disabilities.