This paper uses a typological approach as a tool to establish an analytical framework from a physical perspective to understand ‘place‘ and to identify key spatial characteristics that could adapt to local needs to deliver socio-cultural sustainability. Six representative housing types with their spaces and uses that were introduced in a historic neighborhood in Beijing, China are selected as case studies. Their morphological characteristics at the building, open space and neighborhood scales are examined, and typological transformations among the cases in terms of the degree of spatial continuity are identified. The paper proposes an analytical framework consisting of fifteen indicators to assess socio-cultural sustainability at the different morphological scales (building, open space and block/neighborhood) of the residents of the six cases. The score of changes from its original design is brought into calculations of continuities of spatial characteristics, which present the transitions and transformations of morphological characteristics in relation to adaptation of local needs and uses. The analysis results show that the spatial characteristics were changed when political-socioeconomic ideologies changed, and local needs and uses were transformed to follow these mutations, and finally, the methods of use in different morphological scales mostly differed from historical norms. Although the continuities of spatial characteristics were significantly changed, they are positively and continually accommodating the transformations and transitions of local needs and uses. On the other hand, the invariant spatial characteristics are important, which last despite transformation of the city development and changing of political-social-economic ideologies, and could be maintained for future development to enhance sociocultural sustainability.