Handbook of plant morphology; being the Handbook of plant dissection by J. C. Arthur, Charles R. Barnes and John M. Coulter revised and rewritten by Otis W. Caldwell.

Arthur, J. C.; Barnes, Charles Reid; Caldwell, Otis W.; Coulter, John M.

doi:10.5962/bhl.title.26209

Cited by 18 publications

(22 citation statements)

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“…In distal colon epithelium permeabilized with nystatin, the serosal addition of Gd 3+ (100 mM) aected neither basal I K nor the current induced by thē avonol (Figure 7a,b). The latter experiments were conducted in HEPES/Tris buer due to the fact that Gd 3+ ions can be eectively bound by CO 3 27 and PO 4 37 anions (Caldwell et al, 1998).…”

Section: Quercetin Activates Basolateral K + Channelsmentioning

confidence: 99%

The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium

Cermak

Kuhn

Wolffram

2002

British J Pharmacology

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1 The¯avonol quercetin has been shown to activate a Cl 7 secretion in rat colon. Unlike the secretory activity of the related iso¯avone genistein, quercetin's secretory activity does not depend on cyclic AMP; instead, it depends on Ca 2+ . We investigated the possible involvement of Ca 2+ dependent basolateral K + channels using apically permeabilized rat distal colon epithelium mounted in Ussing chambers. 2 In intact epithelium, quercetin induced an increase in short-circuit current (I sc ), which was diminished by the Cl 7 channel blockers NPPB and DPC, but not by glibenclamide, DIDS or anthracene-9-carboxylic acid. The e ect of the¯avonol was also inhibited by several serosally applied K + channel blockers (Ba 2+ , quinine, clotrimazole, tetrapentylammonium, 293B), whereas other K + channel blockers failed to in¯uence the quercetin-induced increase in I sc (tetraethylammonium, charybdotoxin). 3 The apical membrane was permeabilized by mucosal addition of nystatin and a serosally directed K + gradient was applied. The successful permeabilization was con®rmed by experiments demonstrating the failure of bumetanide to inhibit the carbachol-induced current. 4 In apically permeabilized epithelium, quercetin induced a K + current (I K ), which was neither in¯uenced by ouabain nor by bumetanide. Whereas DPC, NPPB, charybdotoxin and 293B failed to inhibit this I K , quinine, Ba 2+ , clotrimazole and tetrapentylammonium were e ective blockers of this current. 5 We conclude from these results that at least part of the quercetin-induced Cl 7 secretion can be explained by an activation of basolateral K + channels.

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Section: Quercetin Activates Basolateral K + Channelsmentioning

confidence: 99%

The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium

Cermak

Kuhn

Wolffram

2002

British J Pharmacology

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“…In this work it will be shown that like most species of mammals, the African elephant converts benzoic and phenylacetic acid into their glycine conjugates and phenol into its sulphate and glucuronic acid conjugates. In the case of the hyaena phenol, at a level of 10 mg/ kg, forms only sulphate conjugates and is thus similar to the cat, lion, civet and genet and also the caracal [5]. The hyaena also does not acetylate the aromatic amino group of sulphadimethoxine and is in this respect like the domestic dog [6] rather than the cats which acetylate the drug [ 1 ] .…”

Section: Introductionmentioning

confidence: 99%

Conjugation of foreign compounds in the elephant and hyaena

et al. 1975

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“…The intrinsic colours for these stars have been determined using UBV photometric Q method (cf. Johnson & Morgan 1953;Sagar & Joshi 1979) and the calibrations given by Caldwell et al (1993)…”

Section: Interstellar Extinction Towards the Clustersmentioning

confidence: 99%

UBV RICCD photometric study of the open clusters Basel 4 and NGC 7067

Yadav

Sagar

2004

Monthly Notices of the Royal Astronomical Society

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In this paper we present UBV RI CCD photometry in the region of two young open star clusters Basel 4 and NGC 7067 for the first time. Our sample consists of ∼4000 stars down to V∼ 21 mag. Stellar surface density profile indicates that radii of Basel 4 and NGC 7067 are about 1.8 and 3.0 arcmin respectively. The (U−B) versus (B−V) diagrams indicate that the metallicity of NGC 7067 is solar while that of Basel 4 is Z∼ 0.008. We estimate the mean value of E(B−V) = 0.45 ± 0.05 and 0.75 ± 0.05 mag for Basel 4 and NGC 7067, respectively. The analysis of 2MASS JHK data in combination with the optical data in both the clusters yields E(J−K) = 0.30 ± 0.20 mag and E(V−K) = 1.60 ± 0.20 mag for Basel 4 while E(J−K) = 0.40 ± 0.20 mag and E(V−K) = 2.10 ± 0.20 mag for NGC 7067. Furthermore, colour excess diagrams show a normal interstellar extinction law towards both the clusters. Using the intrinsic colour–magnitude diagrams of the cluster members, we estimated the distances of the clusters as 3.0 ± 0.2 and 3.6 ± 0.2 kpc for Basel 4 and NGC 7067, respectively. By fitting the proper metallicity isochrones to the bright cluster members we estimated the age of the clusters as 200 ± 50 and 100 ± 25 Myr for Basel 4 and NGC 7067, respectively. The mass function slopes that are derived by applying the corrections of field star contamination and data incompleteness are 1.55 ± 0.25 and 1.68 ± 0.47 for Basel 4 and NGC 7067, respectively. The values of the mass function slope are thus not very different from Salpeter's value. Mass segregation is observed in both the clusters, which may be caused by the dynamical evolution or the imprint of star formation processes or both.

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Handbook of plant morphology; being the Handbook of plant dissection by J. C. Arthur, Charles R. Barnes and John M. Coulter revised and rewritten by Otis W. Caldwell.

Cited by 18 publications

References 0 publications

The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium

The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium

Conjugation of foreign compounds in the elephant and hyaena

UBV RICCD photometric study of the open clusters Basel 4 and NGC 7067

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Handbook of plant morphology; being the Handbook of plant dissection by J. C. Arthur, Charles R. Barnes and John M. Coulter revised and rewritten by Otis W. Caldwell.

Cited by 18 publications

References 0 publications

The flavonol quercetin activates basolateral K+ channels in rat distal colon epithelium

The flavonol quercetin activates basolateral K+ channels in rat distal colon epithelium

Conjugation of foreign compounds in the elephant and hyaena

UBV RICCD photometric study of the open clusters Basel 4 and NGC 7067

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The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium

The flavonol quercetin activates basolateral K⁺ channels in rat distal colon epithelium