Handgrip Strength Thresholds are Associated With Malnutrition Inflammation Score (MIS) in Maintenance Hemodialysis Patients

Xavier, Jéssica Santos; Góes, Cassiana Regina de; Borges, Mariana Clementoni Costa; Caramori, Jacqueline Costa Teixeira; Vogt, Barbara

doi:10.1053/j.jrn.2022.01.014

Cited by 9 publications

(3 citation statements)

References 27 publications

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“…Excess circulating urea, chronic inflammatory state, and endocrine disorders inherent to CKD make this population more exposed to impaired muscle function [ 32 ]. Uremic toxins increase oxidative stress and can affect mitochondrial metabolism and energy supply to muscle [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

The relationship between grip strength with health-related quality of life and mortality in hemodialysis patients

Sugizaki

Rodrigues

Ivo

et al. 2022

Nutrire

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Purpose Hemodialysis (HD) is a therapeutic modality that enables the highest survival for individuals with chronic kidney disease (CKD). In contrast, HD contributes to the pro-inflammatory state and may negatively affect the muscle strength and quality of life (QoL) of these individuals. To date, few studies have evaluated the association between decrease in strength and QoL in HD patients. Thus, our objective was to assess whether diminished muscle strength is associated with worse health related QoL and mortality. Methods We included patients aged ≥ 18 years on HD. Clinical and demographic data were collected from patients’ medical records. Clinical data, nutritional status (laboratory, anthropometry, bioimpedance analysis) and health-related QoL (World Health Organization’s quality of life questionnaire, WHOQOL-Bref) were analyzed at baseline. Mortality was recorded for 32 months. Results Among the 105 patients evaluated, the median age was 52 (43–64) years, and males were predominant (n = 73; 70%). The general median of QoL was 66.8 ± 11.9. Approximately 30% of patients were considered to have a worse QoL and 12,4% to have low muscle strength. This was not associated with QoL and mortality. HD vintage greater then to 5 years was associated with higher dissatisfaction in the perception of the environmental domain and overall QoL. Conclusion Our data suggest that low muscle strength was not associated with health-related QoL using the WHOQOL-Bref instrument and mortality.

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Section: Discussionmentioning

confidence: 99%

The relationship between grip strength with health-related quality of life and mortality in hemodialysis patients

Sugizaki

Rodrigues

Ivo

et al. 2022

Nutrire

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“…Al Saran et al in Riyadh reported that the cause of chronic renal failure included the following: DN in 82 patients (41%), hypertension in 40 patients (20%), chronic glomerulonephritis in 12 patients (6%), hypoplastic kidney in 4%, lupus nephritis in 3%, unknown etiology in 22%, obstructive uropathy in 2%, and tubulo-interstitial nephritis and contrast-induced nephropathy in 1% each (21). In addition, the main causes of CKD in very recent report were DN (28.4%), followed by hypertensive nephrosclerosis (HN) (19.3%), glomerulonephritis (9.2%), ADPKD (3.7%) and 19.7% undetermined cause (22). Glomerulonephritis (31.7%), HN (26.7%), and DM (16.7%) were reported as the main underlying diseases in the HD group of Rodrigues et al study (23).…”

Section: Nutritional Assessment and Laboratory Findings In Dn Patientsmentioning

confidence: 99%

Underlying diseases, nutritional assessment, viral incidence and HBV immunity status in patients undergoing hemodialysis

et al. 2023

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Introduction: Underlying kidney diseases and their progression cease the function of kidney and raise the need for regular maintenance dialysis. Furthermore, nutritional requirements and blood born viral infections affect their quality of life. Objectives: This study aims to investigate viral incidence, underlying kidney diseases, nutritional status; and hepatitis B virus (HBV) immunity status in hemodialysis (HD) patients. Patients and Methods: A total of 330 end-stage renal disease (ESRD) patients were assessed for human immunodeficiency virus (HIV), HBV, hepatitis C virus (HCV) viruses using Enzyme-linked immunosorbent assay (ELISA) assay. The underlying kidney diseases were confirmed by a physician. Eighty-two subjects with diabetic nephropathy are referred to dietitian for nutritional assessments and body mass index (BMI) measurement. Hepatitis B surface antibody (Anti-HBs) tests were done at two different times of year for 94 qualified subjects. Results: Out of 330 patients 82 (24.8%) had diabetic mellitus (DM), 5 (1.5%) myocardial infarction (MI), 3 (0.9%) systemic lupus erythematosus (SLE), 55 (16.7%) hypertensive nephrosclerosis (HN), 3 (0.9%) obstructive nephropathy, 5 (1.5%) autosomal dominant polycystic kidney disease (ADPKD), and 4 (1.2%) glomerulonephritis. 45 cases (13.6%) had DM and HTN simultaneously. Eleven percent of diabetic nephropathy (DN) patients had severe malnutrition. Only five men (1.51%) were positive for HBV. No incidence of HCV and HIV was seen. Findings showed a dramatic change for anti-HBs after 6 months. Conclusion: Despite the advances in medicine, malnutrition and viral diseases still threaten dialysis patients. DM was the most common underlying disease. The safety of dialysis patients for HBV is compromised after regular dialysis, underscoring the importance of strict adherence to vaccination program.

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“…The MIS was inversely correlated with muscle power as assessed by handgrip strength in patients on HD (mean age: 58.3 years). The MIS was significantly associated with the risk of low handgrip strength (below the cut-off value for sarcopenia; odds ratio (OR) 1.202; 95% CI 1.073–1.347; p < 0.01) and with mortality (OR 1.322; 95% CI 1.192–1.467; p < 0.01), indicating that a worse nutritional status increases the risk of sarcopenia and mortality [ 39 ]. Among patients on PD, there was a significantly higher MIS in those with physical frailty than in those without (7.13 ± 3.22 vs. 5.12 ± 2.30, p < 0.01).…”

Section: Association Of Malnutrition With Sarcopenia and Frailtymentioning

confidence: 99%

Recent Advances in the Nutritional Screening, Assessment, and Treatment of Japanese Patients on Hemodialysis

Ishida

Kato

2023

JCM

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Patients on hemodialysis (HD) have a higher rate of protein-energy wasting (PEW) due to lower dietary intake of energy and protein (particularly on dialysis days) and greater loss of many nutrients in the dialysate effluent than other patients. The most well-known method of nutritional screening is the subjective global assessment. Moreover, the Global Leadership Initiative on MalnutIrition has developed the first internationally standardized method for diagnosing malnutrition; however, its use in patients on HD has not been established. In contrast, the nutritional risk index for Japanese patients on HD has recently been developed as a screening tool for malnutrition in patients on HD, based on the modified PEW criteria. These tools are beneficial for screening nutritional disorders, enabling registered dietitians to assess patients’ dietary intake on dialysis and non-dialysis days and provide advice on dietary intake, especially immediately after dialysis cessation. Oral supplementation with enteral nutrients containing whey protein may also be administered when needed. In patients that experience adverse effects from oral supplementation, intradialytic parenteral nutrition (IDPN) should be combined with moderate dietary intake because IDPN alone cannot provide sufficient nutrition.

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Handgrip Strength Thresholds are Associated With Malnutrition Inflammation Score (MIS) in Maintenance Hemodialysis Patients

Cited by 9 publications

References 27 publications

The relationship between grip strength with health-related quality of life and mortality in hemodialysis patients

The relationship between grip strength with health-related quality of life and mortality in hemodialysis patients

Underlying diseases, nutritional assessment, viral incidence and HBV immunity status in patients undergoing hemodialysis

Recent Advances in the Nutritional Screening, Assessment, and Treatment of Japanese Patients on Hemodialysis

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