An increasing proportion of Hansen disease cases in the United States occurs
among migrants from the Micronesian region, where leprosy prevalence is high. We
abstracted surveillance and clinical records of the National Hansen’s
Disease Program to determine geographic, demographic, and clinical patterns.
Since 2004, 13% of US cases have occurred in this migrant population. Although
Hawaii reported the most cases, reports have increased in the central and
southern states. Multibacillary disease in men predominates on the US mainland.
Of 49 patients for whom clinical data were available, 37 (75%) had leprosy
reaction, neuropathy, or other complications; 17 (37%) of 46 completed
treatment. Comparison of data from the US mainland with Hawaii and
country-of-origin suggests under-detection of cases in pediatric and female
patients and with paucibacillary disease in the United States. Increased case
finding and management, and avoidance of leprosy-labeled stigma, is needed for
this population.