Hantavirus Pulmonary Syndrome Associated with Entering or Cleaning Rarely Used, Rodent-Infested Structures

Armstrong, Lori; Zaki, Sherif R.; Goldoft, Marcia; Todd, Randall L.; Khan, Ali S.; Khabbaz, Rima F.; Ksiazek, Thomas G.; Peters, C. J.

doi:10.1093/infdis/172.4.1166

Cited by 85 publications

(56 citation statements)

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“…As other risk-factor studies have shown, cleaning of sheds and shelters was also associated with a high risk of PUUV infection in our case-control study [26]. An explanation could be that sheds and shelters are rarely used and are therefore more likely to be infested with bank voles.…”

Section: Discussionsupporting

confidence: 64%

Survey and case-control study during epidemics of Puumala virus infection

et al. 2009

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SUMMARYIn Baden-Wuerttemberg, a federal state in south-west Germany, a large outbreak of 1089 laboratory-confirmed human Puumala virus (PUUV) infections occurred in 2007. We conducted a survey to describe the disease burden and a case-control study to identify risk factors for acquiring PUUV. Case-patients were interviewed about clinical outcome and both case-patients and randomly recruited controls were interviewed about exposure. We calculated matched odds ratios (mOR) using a conditional logistic regression model. Multivariable analysis of 191 matched case-control pairs showed that case-patients were more likely than controls to have seen small rodents/their droppings (mOR 1 . 9, 95 % CI 1 . 2-3 . 0), cleaned utility rooms (mOR 1 . 8, 95 % CI 1 . 0-3 . 4) and visited forest shelters (mOR 3 . 9, 95% CI 1 . 1-14 . 3). Two thirds of case-patients required hospitalization. During PUUV epidemics rodent control measures and use of protective equipment should be considered in utility rooms and shelters.

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Section: Discussionsupporting

confidence: 64%

Survey and case-control study during epidemics of Puumala virus infection

et al. 2009

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“…Viruses investigated have included hantaviruses (the agents of haemorrhagic fever with renal syndrome (HFRS); Blasdell et al 2011), lymphocytic choriomeningitis virus (LCMV; Nitatpattana et al 2000) and rabies virus (Brown et al 1979). All these viruses can be transmitted directly between rodent hosts, although transmission of hantaviruses and LCMV likely also occurs through exposure to aerosolised infectious excretions (Monath 1975;Armstrong et al 1995). Among the bacteria, three genera in particular have been a major focus: Leptospira spp., agents of leptospirosis (Thaipadungpanit et al 2007;Ivanova et al 2012;Cosson et al 2014); Bartonella spp., agents of bartonellosis (Castle et al 2004;Saisongkorh et al 2009;Jiyipong et al 2012Jiyipong et al , 2015; and Orientia tsutsugamushi (Coleman et al 2003), the agent of scrub typhus.…”

Section: Identifying Rodent-borne Diseases In Rodentsmentioning

confidence: 99%

Progress on research on rodents and rodent-borne zoonoses in South-east Asia

et al. 2015

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Abstract. This review aims to synthesise knowledge regarding the taxonomy of South-east Asian murine rodents and the challenges associated with the identification of habitat preferences and associated rodent-borne diseases. Recent studies concerning the Rattini tribe have identified unclear species boundaries that would benefit from further investigation. The development of barcoding may allow more accurate identification of rodents, specifically for complex species. However, knowledge on the distribution and habitat specialisations of many common murine rodents is still scarce, particularly regarding the specific habitat preferences of most synanthropic rodent species (Rattus tanezumi or Rattus exulans). Several studies have analysed the prevalence of major rodent-borne diseases in South-east Asia and it appears that the greatest risk of rodent zoonoses are in the lowland rain-fed and irrigated landscapes, generally in and around rice fields.

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“…Aux États-Unis, des études cas-témoins ont révélé que le nettoyage péridomestique, les activités agricoles et une augmentation du nombre de petits mammifères au sein des ménages étaient des facteurs de risque de syndrome pulmonaire à hantavirus (19,20), tout comme le fait d'entrer dans des structures rarement utilisées infestées de rongeurs ou de nettoyer ces lieux (21). Les composantes clés de la prévention se concentrent sur la manipulation sûre des rongeurs, la désinfection et les méthodes d'exclusion des rongeurs (22), et la prévention de la maladie passe principalement par l'éducation du public.…”

Section: Facteurs De Risque Et Préventionunclassified