Happy Heart Syndrome

Stiermaier, Thomas; Walliser, Alexandra; El‐Battrawy, Ibrahim; Pätz, Toni; Mezger, Matthias; Rawish, Elias; Andrés, Mireia; Almendro‐Delia, Manuel; Martínez‐Sellés, Manuel; Uribarri, Aitor; Castellanos, Alberto Pérez; Guerra, Federico; Novo, Giuseppina; Mariano, Enrica; Musumeci, Beatrice; Arcari, Luca; Cacciotti, Luca; Montisci, Roberta; Akın, İbrahim; Thiele, Holger; Brunetti, Natale Daniele; Gil, Iván J. Núñez; Santoro, Francesco; Eitel, Ingo

doi:10.1016/j.jchf.2022.02.015

Cited by 23 publications

(9 citation statements)

References 20 publications

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“…This case also reminds us that when patients after PCI experience unexplained electrocardiogram changes and elevated troponin, we cannot ignore the possibility of TTS while considering the complications after PCI. Additionally, TTS caused by emotional stimulation is not rare, especially under the in uence of negative emotional events [10][11][12]. In the perioperative period of patients receiving interventional therapy, good physician-patient communication is particularly signi cant.…”

Section: Discussionmentioning

confidence: 99%

Case report: Takotsubo syndrome following percutaneous coronary intervention

Li¹,

Wang²,

He³

et al. 2023

Preprint

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Background Takotsubo syndrome (TTS), which is frequently secondary to severe emotional (fear, anxiety, etc.) or physical stress, is an acute reversible heart failure syndrome characterized by temporary left ventricular regional systolic dysfunction. Nevertheless, TTS after percutaneous coronary intervention (PCI) is rare, and its clinical characteristics are easily confused with complications after PCI. Case presentation This article reports a case of TTS induced by psychological and physical pressure after successful PCI in our institution. She had symptoms comparable to complications after PCI, including electrocardiogram (ECG) deviation and troponin elevation. Coronary angiogram, left ventricle contrast echocardiography (LVO), and cardiac magnetic resonance (CMR) were performed to exclude postoperative complications. Definite diagnosis of TTS was eventually achieved. Conclusion We cannot dismiss the risk of TTS in patients who have unexplained ECG deviation and troponin elevation following successful PCI. Meanwhile, medical personnel should provide mental, cultural, and emotional services to patients in addition to essential diagnostic and treatment technical services during the perioperative period.

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Section: Discussionmentioning

confidence: 99%

Case report: Takotsubo syndrome following percutaneous coronary intervention

Li¹,

Wang²,

He³

et al. 2023

Preprint

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“…The two primary studies included in the pooled analysis were those by Stiermaier et al [ 7 ] and Ghadri et al [ 6 ], encompassing 1395 patients with TTC. Of these, 57 were classified under HHS and 1338 under BHS.…”

Section: Reviewmentioning

confidence: 99%

“…In the Stiermaier et al study [ 7 ], the median age for BHS patients was 70 years (IQR: 61-77), while it was 69 years (IQR: 62-78) for HHS patients. In contrast, the Ghadri et al study [ 6 ] reported the mean age of BHS patients as 65 years (SD: ± 12.5 years) and 71.4 years (SD: ± 11.2 years) for HHS patients.…”

Section: Reviewmentioning

confidence: 99%

“…ST segment changes on the EKG were also comparable between HHS and BHS (67% vs. 70%) and were not a risk factor for HHS. The left ventricular ejection fraction values in the Stiermaier et al study [ 7 ] were as follows: median: 43 (IQR: 31-45) for HHS and 40 (IQR: 35-45) for BHS. In contrast, Ghadri et al [ 6 ] reported it in means with standard deviations: 40.2 ± 9.4 for HHS and 42.6 ± 11 for BHS patients.…”

Section: Reviewmentioning

confidence: 99%

“…However, despite its clinical significance, a gap remains in comparative analyses of cardiomyopathic events triggered by positive versus negative emotional valences. Insights from two extensive registry studies have shed light on the potential differential impacts of this variation on patient presentation and outcomes [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

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A Comparative Analysis of Positive and Negative Stimuli for Takotsubo Cardiomyopathy: A Pooled Analysis of Two Studies and a Systematic Review

Mahadevan,

Borra,

Prasanna Vaishnavi Kattamuri

et al. 2024

Cureus

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Takotsubo cardiomyopathy (TTC) is characterized by transient myocardial dysfunction triggered by both negative and positive emotional experiences, known respectively as broken heart syndrome (BHS) and happy heart syndrome (HHS). Despite the scarcity of comparative analyses between HHS and BHS in the literature, our pooled analysis, incorporating two retrospective registry analyses of 1395 TTC patients (57 HHS and 1338 BHS), reveals that while BHS is more prevalent, both conditions exhibit similar clinical presentations and outcomes. Statistical analyses, utilizing binary random effects models, indicate that diabetes mellitus is less common in HHS patients and serves as a predictor for BHS. Furthermore, there are differences in cardiac imaging between the two groups; individuals with HHS have higher odds of experiencing midventricular ballooning, whereas those with BHS are more likely to have apical ballooning. These findings highlight the similarities in clinical features and outcomes between HHS and BHS, while also illustrating distinct imaging profiles. The study emphasizes the need for future prospective studies to delve deeper into the implications of these TTC subtypes, offering valuable insights into their comparative aspects and underlying mechanisms.

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Takotsubo Syndrome

Ratneswaren,

Kaski

2024

Manual of Cardiovascular Disease in Women

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Happy Heart Syndrome

Cited by 23 publications

References 20 publications

Case report: Takotsubo syndrome following percutaneous coronary intervention

Case report: Takotsubo syndrome following percutaneous coronary intervention

A Comparative Analysis of Positive and Negative Stimuli for Takotsubo Cardiomyopathy: A Pooled Analysis of Two Studies and a Systematic Review

Takotsubo Syndrome

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