Sexual harassment is an epidemic throughout global higher education systems and impact individuals, groups and entire organizations in profound ways. Precarious working conditions, hierarchical organizations, a normalization of gender-based violence, toxic academic masculinities, a culture of silence and a lack of active leadership are all key features enabling sexual harassment. The aim of this study is to review scientific knowledge on sexual harassment in higher education. A thematic focus is on (a) knowledge derived from top-ranked peer-reviewed articles in the research field, (b) the prevalence of sexual harassment among students and staff, (c) reported consequences of sexual harassment, (d) examples of primary, secondary and tertiary preventive measures, and (e) core challenges to research on sexual harassment in higher education. The published research evidence suggests several findings of importance, mainly: (a) prevalence of sexual harassment among students is reported by on average one out of four female students; (b) severe consequences of sexual harassment impacts individuals but the effects on the quality in research and education is unknown; (c) there is almost no evidence supporting the supposed effects of major preventive measures; and (d) research on sexual harassment in higher education lacks theoretical, longitudinal, qualitative and intersectional approaches and perspectives.