Hard x-ray phase contrast imaging using a tabletop Talbot–Lau interferometer with multiline embedded x-ray targets

Shimura, Takayoshi; Morimoto, Naoki; Fujino, Sho; Nagatomi, T.; Oshima, Koichiro; Harada, J.; Omote, Kazuhiko; Osaka, Naohisa; Hosoi, Takuji; Watanabe, Heiji

doi:10.1364/ol.38.000157

Cited by 25 publications

(17 citation statements)

References 8 publications

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“…During the last few decades several PC-CT methods have been developed, which are based on crystal interferometer [1–3], free propagation or inline holographic technique [4–7] or diffraction enhancement [8–10]. One of the recent developments is differential PC-CT (DPC-CT), based on a grating interferometer [11–21]. DPC-CT has first been implemented at x-ray synchrotron radiation sources [11–14] and recently transferred to lab-based x-ray tube sources [15–21].…”

Section: Introductionmentioning

confidence: 99%

“…One of the recent developments is differential PC-CT (DPC-CT), based on a grating interferometer [11–21]. DPC-CT has first been implemented at x-ray synchrotron radiation sources [11–14] and recently transferred to lab-based x-ray tube sources [15–21]. Several experimental studies reported in the literature have demonstrated that DPC-CT offers improved soft-tissue contrast compared to the conventional absorption-contrast CT [16–17, 19, 20].…”

Section: Introductionmentioning

confidence: 99%

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3D Algebraic Iterative Reconstruction for Cone-Beam X-Ray Differential Phase-Contrast Computed Tomography

Velroyen

et al. 2015

PLoS ONE

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Due to the potential of compact imaging systems with magnified spatial resolution and contrast, cone-beam x-ray differential phase-contrast computed tomography (DPC-CT) has attracted significant interest. The current proposed FDK reconstruction algorithm with the Hilbert imaginary filter will induce severe cone-beam artifacts when the cone-beam angle becomes large. In this paper, we propose an algebraic iterative reconstruction (AIR) method for cone-beam DPC-CT and report its experiment results. This approach considers the reconstruction process as the optimization of a discrete representation of the object function to satisfy a system of equations that describes the cone-beam DPC-CT imaging modality. Unlike the conventional iterative algorithms for absorption-based CT, it involves the derivative operation to the forward projections of the reconstructed intermediate image to take into account the differential nature of the DPC projections. This method is based on the algebraic reconstruction technique, reconstructs the image ray by ray, and is expected to provide better derivative estimates in iterations. This work comprises a numerical study of the algorithm and its experimental verification using a dataset measured with a three-grating interferometer and a mini-focus x-ray tube source. It is shown that the proposed method can reduce the cone-beam artifacts and performs better than FDK under large cone-beam angles. This algorithm is of interest for future cone-beam DPC-CT applications.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

3D Algebraic Iterative Reconstruction for Cone-Beam X-Ray Differential Phase-Contrast Computed Tomography

Velroyen

et al. 2015

PLoS ONE

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“…In the hard x-ray regime, phase contrast imaging is the primary contrast-generating mechanism because that samples generally are more transparent. A variety of phase sensitive techniques have been implemented for lens-based full-field x-ray microscopes including both Zernike phase contrast 7-12 and others promising phase contrast imaging methods [13][14][15][16][17][18] .…”

Section: Introductionmentioning

confidence: 99%

Apodized photon sieves for phase-contrast nano-imaging of living cells

Cheng

Hong

et al. 2013

Optical Methods for Inspection, Characterization, and Imaging of Biomaterials

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We present a type of diffractive lenses "Zernike apodized photon sieves" (ZAPS), which structure is based on the combination of two concepts: apodized photon sieves and Zernike phase-contrast. In combination with the synchrotron light sources, the ZAPS can be used as an objective for high-resolution X-ray phase-contrast microscopy in physical and life sciences. The ZAPS is a single optic that integrates the appropriate ±π/2 radians phase shift through selective zone placement shifts in an apodized photon sieve. The focusing properties of the ZAPS can be easily controlled by apodizing its pupil function. An apodized photon sieve with Gaussian pupil was fabricated by lithographic technique and showed that the side-lobes have been significantly suppressed at the expense of slightly widening the width of the main lobe.

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“…1(b)] [4]. When electrons were irradiated on the targets, x rays were generated by both the metal multilines and the diamond substrate.…”

mentioning

confidence: 99%

“…We can easily fabricate multiline targets of less than 10 μm by conventional photolithography and reactive ion etching (RIE) processes. In our previous study, we fabricated an array of linear x-ray sources of 5 μm line width and achieved XPCI with high power efficiency and source-detector distances for Cu and Mo targets of 45-90 cm, respectively [4].…”

mentioning

confidence: 99%

X-ray phase contrast imaging by compact Talbot–Lau interferometer with a single transmission grating

et al. 2014

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We performed x-ray phase contrast imaging (XPCI) by Talbot-Lau interferometer using only a single transmission grating. Multiline metal targets embedded in a diamond substrate were irradiated with electrons to generate an array of x-ray lines of 1 μm width, which allowed XPCI within a 1 m source-detector distance in a configuration without a source or absorption grating. We directly resolved the self-image of the phase grating of 3 μm pitch using an x-ray image detector of 24 μm pixel size and successfully obtained absorption, differential phase, and dark-field images for 8 keV x rays.

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Hard x-ray phase contrast imaging using a tabletop Talbot–Lau interferometer with multiline embedded x-ray targets

Cited by 25 publications

References 8 publications

3D Algebraic Iterative Reconstruction for Cone-Beam X-Ray Differential Phase-Contrast Computed Tomography

3D Algebraic Iterative Reconstruction for Cone-Beam X-Ray Differential Phase-Contrast Computed Tomography

Apodized photon sieves for phase-contrast nano-imaging of living cells

X-ray phase contrast imaging by compact Talbot–Lau interferometer with a single transmission grating

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