Harmful alcohol use among injured adult patients presenting to a Ghanaian emergency department

Gardner, Andrew J.; Forson, Paa Kobina; Oduro, George; Djan, Doreen; Adu, Kwame Ofori; Ofori-Anti, Kwasi; Maio, Ronald F.

doi:10.1136/injuryprev-2016-042104

Cited by 8 publications

(12 citation statements)

References 12 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There were only 6 car drivers in this study, and 76% of the injured road users were motorcyclists (Damsere-Derry et al 2018). In another study where 1085 road traffic injury patients were investigated, it was found that 42% of both drivers and pedestrians tested positive for alcohol (Forson et al 2017). In a study from the Ivory Coast they performed blood alcohol testing in the emergency department on 672 patients (Diakite et al 2014).…”

Section: Introductionmentioning

confidence: 87%

“…Our results resemble those from Uganda (Biribawa et al 2019), where the pedestrians had a much higher prevalence of alcohol use than drivers. The one Ghanaian study with an adequate number of car drivers shows a different pattern, with approximately the same prevalence in pedestrians and drivers (Forson et al 2017). In Ivory Coast, drivers also had a higher prevalence among drivers compared to pedestrians (Diakite et al 2014).…”

Section: Prevalence (95% Ci)mentioning

confidence: 99%

See 1 more Smart Citation

Prevalence of alcohol use among road traffic crash victims presenting to a Malawian Central Hospital: A cross-sectional study

Sundet

Kajombo

Mulima

et al. 2020

Traffic Injury Prevention

View full text Add to dashboard Cite

Background: Alcohol consumption is a well-known risk factor for sustaining road traffic injuries worldwide. Malawi is a low-income country with a large and increasing burden of road traffic injuries. It has generally been viewed as a country with relatively little alcohol consumption. This study investigates the role of alcohol in road traffic injuries in and around the capital Lilongwe. Methods: All patients presenting to the emergency department of Kamuzu Central Hospital after being injured in road traffic crashes were asked to participate in the study. Alcohol testing was done with a breathalyzer or a saliva test. Participants were asked about alcohol use before the injury as well as hazardous drinking using the AUDIT-C questionnaire. Results: Of 1347 patients age 18 years or older who were asked to participate, 1259 gave informed consent, and data on alcohol use (alcohol test results and/or self-reported intake) were available for 1251 participants. Of those, 251 (20.1%) tested positive for alcohol, whereas 221 (17.7%) reported alcohol use before the crash; in total 311 (24.9%, 95% CI 22.5-27.3) either tested positive, reported use, or both. Females had a low prevalence of alcohol use (2.5%), while 30.6% of males had consumed alcohol before the injuries. Pedestrians had the highest prevalence at 41.8% (95% CI 35.5-48.4), while car drivers had 23.8% (95% CI 18.2-30.5). Among male pedestrians, 49.5% had used alcohol before the injury. Alcohol-associated injuries had a peak in the evening and at night, especially in the weekends. Of the patients, 63.1% reported that they had not consumed alcohol during the last year, while 21.4% had an AUDIT-C score suggesting hazardous drinking, and 66.2% of those had used alcohol before the injury. Conclusions: A large percentage of road traffic injured patients had been drinking alcohol before their injury, especially male pedestrians. A large proportion of the patients were abstaining from alcohol, but those not abstaining had a high prevalence both of alcohol use when injured and hazardous drinking identified by AUDIT-C. This has important implications for prevention.

show abstract

Section: Introductionmentioning

confidence: 87%

Section: Prevalence (95% Ci)mentioning

confidence: 99%

Prevalence of alcohol use among road traffic crash victims presenting to a Malawian Central Hospital: A cross-sectional study

Sundet

Kajombo

Mulima

et al. 2020

Traffic Injury Prevention

View full text Add to dashboard Cite

show abstract

“…Alcohol is a nearly globally consumed drug that is widely socially accepted. Given that up to 50% of trauma-related injuries occur under the influence of alcohol, it is critical to consider its interaction with general anesthetics 1 – 3 . The effects of alcohol are dose dependent.…”

Section: Discussionmentioning

confidence: 99%

“…Alcohol is a global contributor to numerous diseases and is associated with a vast number of trauma-related injuries 1 – 3 . It shows dose dependent stimulative or sedative effects but when consumed in higher quantities central nervous system depressive effects become more pronounced 4 .…”

Section: Introductionmentioning

confidence: 99%

Ethanol reduces the minimum alveolar concentration of sevoflurane in rats

Müller

Plöchl

Mühlbacher

et al. 2022

Sci Rep

View full text Add to dashboard Cite

A high number of trauma patients are under the influence of alcohol. Since many of them need immediate surgical procedures, it is imperative to be aware of the interaction of alcohol with general anesthesia. To counter challenges that arise from clinical studies, we designed an animal experiment in which 48 adult Wistar rats either received 1 g · kg−1 ethanol, 2 g · kg−1 ethanol or placebo via intraperitoneal application. Subsequently, they were anesthetized with an individual concentration of sevoflurane. The minimum alveolar concentration (MAC) of the different groups was assessed using Dixon’s up-and-down design and isotonic regression methods. The bootstrap estimate of the MAC of sevoflurane in the placebo group was 2.24 vol% (95% CI 1.97–2.94 vol%). In the low dose ethanol group, the bootstrap estimate was 1.65 vol% (95% CI 1.40–1.98 vol%), and in the high dose ethanol group, it was 1.08 vol% (95% CI 0.73–1.42 vol%). We therefore report that intraperitoneal application of 1 g · kg−1 or 2 g · kg−1 ethanol both resulted in a significant reduction of the MAC of sevoflurane in adult Wistar rats: by 26.3% and 51.8% respectively as compared to placebo.

show abstract

“…In Africa, for example, an estimated 70% of countries lack access to vital or civil registration homicide data, which greatly impedes research on the burden of IPVRI and its associated risk factors. 2 To fill this gap, recent research has used hospital-level [17][18][19][20][21][22][23][24][25][26][27][28] or demographic survey [29][30][31][32][33][34] data to better characterise the burden of IPVRI in sub-Saharan Africa. There remains a need for further research on IPVRI, though, as many of these studies have been limited by small sample size, a broad definition of interpersonal violence, lack of focus on risk and protective factors or absence of a control group.…”

Section: Bmj Global Healthmentioning

confidence: 99%

Associations between social determinants of health and interpersonal violence-related injury in Cameroon: a cross-sectional study

et al. 2022

View full text Add to dashboard Cite

IntroductionRisk factors for interpersonal violence-related injury (IPVRI) in low-income and middle-income countries (LMICs) remain poorly defined. We describe associations between IPVRI and select social determinants of health (SDH) in Cameroon.MethodsWe conducted a cross-sectional analysis of prospective trauma registry data collected from injured patients >15 years old between October 2017 and January 2020 at four Cameroonian hospitals. Our primary outcome was IPVRI, compared with unintentional injury. Explanatory SDH variables included education level, employment status, household socioeconomic status (SES) and alcohol use. The EconomicClusters model grouped patients into household SES clusters: rural, urban poor, urban middle-class (MC) homeowners, urban MC tenants and urban wealthy. Results were stratified by sex. Categorical variables were compared via Pearson’s χ2 statistic. Associations with IPVRI were estimated using adjusted odds ratios (aOR) with 95% confidence intervals (95%CI).ResultsAmong 7605 patients, 5488 (72.2%) were men. Unemployment was associated with increased odds of IPVRI for men (aOR 2.44 (95% CI 1.95 to 3.06), p<0.001) and women (aOR 2.53 (95% CI 1.35 to 4.72), p=0.004), as was alcohol use (men: aOR 2.33 (95% CI 1.91 to 2.83), p<0.001; women: aOR 3.71 (95% CI 2.41 to 5.72), p<0.001). Male patients from rural (aOR 1.45 (95% CI 1.04 to 2.03), p=0.028) or urban poor (aOR 2.08 (95% CI 1.27 to 3.41), p=0.004) compared with urban wealthy households had increased odds of IPVRI, as did female patients with primary-level/no formal (aOR 1.78 (95% CI 1.10 to 2.87), p=0.019) or secondary-level (aOR 1.54 (95% CI 1.03 to 2.32), p=0.037) compared with tertiary-level education.ConclusionLower educational attainment, unemployment, lower household SES and alcohol use are risk factors for IPVRI in Cameroon. Future research should explore LMIC-appropriate interventions to address SDH risk factors for IPVRI.

show abstract

Harmful alcohol use among injured adult patients presenting to a Ghanaian emergency department

Cited by 8 publications

References 12 publications

Prevalence of alcohol use among road traffic crash victims presenting to a Malawian Central Hospital: A cross-sectional study

Prevalence of alcohol use among road traffic crash victims presenting to a Malawian Central Hospital: A cross-sectional study

Ethanol reduces the minimum alveolar concentration of sevoflurane in rats

Associations between social determinants of health and interpersonal violence-related injury in Cameroon: a cross-sectional study

Contact Info

Product

Resources

About