2024
DOI: 10.1097/coh.0000000000000840
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Harnessing immune cells to eliminate HIV reservoirs

Paula Grasberger,
Abigail R. Sondrini,
Kiera L. Clayton

Abstract: Purpose of review Despite decades of insights about how CD8+ T cells and natural killer (NK) cells contribute to natural control of infection, additional hurdles (mutational escape from cellular immunity, sequence diversity, and hard-to-access tissue reservoirs) will need to be overcome to develop a cure. In this review, we highlight recent findings of novel mechanisms of antiviral cellular immunity and discuss current strategies for therapeutic deisgn. Recent find… Show more

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Cited by 3 publications
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