2024
DOI: 10.3233/jad-231010
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Harnessing Passive Pulsatile Shear Stress for Alzheimer’s Disease Prevention and Intervention

Jose A. Adams,
Arkady Uryash,
Jose R. Lopez

Abstract: Alzheimer’s disease (AD) affects more than 40 million people worldwide and is the leading cause of dementia. This disease is a challenge for both patients and caregivers and puts a significant strain on the global healthcare system. To address this issue, the Lancet Commission recommends focusing on reducing modifiable lifestyle risk factors such as hypertension, diabetes, and physical inactivity. Passive pulsatile shear stress (PPSS) interventions, which use devices like whole-body periodic acceleration, peri… Show more

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