2024
DOI: 10.1101/2024.01.24.577087
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Harnessing the diversity ofBurkholderiaspp. prophages for therapeutic potential

Hayley R. Nordstrom,
Marissa P. Griffith,
Vatsala Rangachar Srinivasa
et al.

Abstract: Burkholderia spp. are often resistant to antibiotics, and infections with these organisms are difficult to treat. A potential alternative treatment for Burkholderia spp. infections is bacteriophage (phage) therapy; however, it can be difficult to locate phages that target these bacteria. Prophages incorporated into the bacterial genome have been identified within Burkholderia spp. and may represent a source of useful phages for therapy. Here we investigate whether prophages within Burkholderia spp. clinical is… Show more

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