Harvesting microalgae for health beneficial dietary supplements

Laamanen, Corey A.; Desjardins, Sabrina Marie; Senhorinho, Gerusa N.A.; Scott, John A.

doi:10.1016/j.algal.2021.102189

Cited by 35 publications

(20 citation statements)

References 102 publications

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“…Cell disruption due to gravitational and shear forces may cause the loss of valuable products in the medium, representing a disadvantage in producing high-end products. [215] A study has reported that increasing centrifugal force above 5000 g causes cell disruption and an overall 40% loss in glycerol content in D. salina. [216] Flotation relies on transferring the cells to the medium's surface, from which they can be skimmed.…”

Section: Biomass Harvestingmentioning

confidence: 99%

“…However, these chemical flocculants are influenced by the pH of the system and have been associated with negative health effects such as cancer and Alzheimer's disease. [215] Considering this, their use in cell recovery for nutraceuticals is not recommended due to possible contamination. Furthermore, using these chemical flocculants prevents the reuse of the media.…”

Section: Biomass Harvestingmentioning

confidence: 99%

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Microalgae as sources of green bioactives for health-enhancing food supplements and nutraceuticals: A review of literature

Bhagea

Hossen

Ruhee

et al. 2022

AJBPS

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The world population is ever increasing and so is the need to ensure food security. Food production needs to increase by about 70% within the next 40 years to cater for food consumption. Moreover, with increasing collective consciousness toward food supplementation for improving quality of health, the development of nutraceuticals has gained prominence in disease prevention, treatment, and overall health improvement. However, due to the constant controversial debate of food production for consumption against other uses, the search for better alternatives led to microalgae. Species such as Spirulina, Chlorella, Scenedesmus, and Dunaliella, among many others, are important sources of primary and secondary metabolites that play crucial roles in disease prevention and treatment. Understanding the significance of nutraceuticals and how microalgae can be used to produce those value-added molecules is necessary for any potential commercial exploitation. This review discusses the potential of microalgae to be exploited as promising sources of nutraceuticals. Here, essential biomolecules used as nutraceuticals are explored and their crucial roles in disease prevention, especially cancer, cardiovascular diseases, and strengthening the immune system. The composition of microalgae, which makes them suitable candidates to produce nutraceuticals, is discussed. Furthermore, the multifarious aspects of microalgae cultivation, in terms of cultivation systems and factors affecting biomass production and productivity regarding nutraceutical production, are reviewed. The multiple sustainable facets of microalgae culture, which can help in carbon sequestration, fast biomass production, and boosting health benefits, should interest stakeholders and potential commercial producers. Bioprocessing of microalgae for the extraction and purification of microalgae-based products is also reviewed, focusing on the key methods of pre-treatment, extraction, and purification of microalgal biomass.

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Section: Biomass Harvestingmentioning

confidence: 99%

Section: Biomass Harvestingmentioning

confidence: 99%

Microalgae as sources of green bioactives for health-enhancing food supplements and nutraceuticals: A review of literature

Bhagea

Hossen

Ruhee

et al. 2022

AJBPS

View full text Add to dashboard Cite

show abstract

“…Membrane filtration is seen as a promising method for the recovery of proteins from microalgae not only because of its green nature (since no contaminating chemicals are required), but also because it may preserve both their functional and nutritional properties, which become particularly relevant in the production of health beneficial products [ 94 , 95 ]. The recovery of target proteins usually involves the use of multi-step membrane processes to achieve a high yield and purity.…”

Section: Membrane Technology For the Downstream Processing Of Valuable Products Derived From Microalgal Biomassmentioning

confidence: 99%

“…The PVDF membrane showed very low protein binding capacity, minimizing unspecific protein binding on the membrane while allowing its reusability through multiple filtration cycles. Moreover, the membrane was able to retain—selectively and reversibly—phycobiliproteins (which have shown health benefits such as antioxidant, anti-inflammatory, anti-cancer, and anti-viral activities [ 95 ]) via a tailored ammonium sulphate precipitation. Ultrafiltration in the diafiltration mode assisted with ammonium sulphate precipitation has also been reported for the purification of R-phycoerythrin from Gelidium pusillum (68% yield and a purity index of 0.49), which has a market value of 180–250 USD/mg and commercial applications in immunology, diagnostics, cosmetics and foods [ 102 ].…”

Section: Membrane Technology For the Downstream Processing Of Valuable Products Derived From Microalgal Biomassmentioning

confidence: 99%

Membrane-Based Harvesting Processes for Microalgae and Their Valuable-Related Molecules: A Review

Castro-Muñoz

García‐Depraect

2021

Membranes

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The interest in microalgae production deals with its role as the third generation of feedstock to recover renewable energy. Today, there is a need to analyze the ultimate research and advances in recovering the microalgae biomass from the culture medium. Therefore, this review brings the current research developments (over the last three years) in the field of harvesting microalgae using membrane-based technologies (including microfiltration, ultrafiltration and forward osmosis). Initially, the principles of membrane technologies are given to outline the main parameters influencing their operation. The main strategies adopted by the research community for the harvesting of microalgae using membranes are subsequently addressed, paying particular attention to the novel achievements made for improving filtration performance and alleviating fouling. Moreover, this contribution also gives an overview of the advantages of applying membrane technologies for the efficient extraction of the high added-value compounds in microalgae cells, such as lipids, proteins and carbohydrates, which together with the production of renewable biofuels could boost the development of more sustainable and cost-effective microalgae biorefineries.

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“…Microalgae are rich natural sources of carbohydrates, protein, fiber, and enzymes and have significant amounts of B and A vitamins, omega 3 fatty acids, as well as numerous minerals such as iodine, potassium, iron, magnesium, and calcium. On the other hand, they are very low in calories and can be used as dietary supplements in various diets (Laamanen et al 2021 ). Among microalgae, the species Chlorella vulgaris , Haematococcus pluvialis , Spirulina platensis , Dunaliella salina , and Aphanizomenon are now widely used around the world to make food supplements for humans and as a nutrient additive to animal feed (Hemantkumar and Rahimbhai 2019 ; Nicoletti 2016 ).…”

Section: Introductionmentioning

confidence: 99%

Recent advances in the bio-application of microalgae-derived biochemical metabolites and development trends of photobioreactor-based culture systems

Khaligh

Asoodeh

2022

3 Biotech

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Microalgae are microscopic algae in sizes ranging from a few micrometers to several hundred micrometers. On average, half of the oxygen in the atmosphere is produced by the photosynthetic process of microalgae, so the role of these microorganisms in the life cycle of the planet is very significant. Pharmaceutical products derived from microalgae and commercial developments of a variety of supplements extracted from them originate from a variety of their specific secondary metabolites. Many of these microalgae are a reservoir of unique biological compounds including carotenoids, antioxidants, fatty acids, polysaccharides, enzymes, polymers, peptides, pigments, toxins and sterols with antimicrobial, antiviral, antifungal, antiparasitic, anticoagulant, and anticancer properties. The present work begins with an introduction of the importance of microalgae in renewable fuels and biodiesel production, the development of healthy food industry, and the creation of optimal conditions for efficient biomass yield. This paper provides the latest research related to microalgae-derived substances in the field of improving drug delivery, immunomodulatory, and anticancer attributes. Also, the latest advances in algal biocompounds to combat the COVID-19 pandemic are presented. In the subject of cultivation and growth of microalgae, the characteristics of different types of photobioreactors, especially their latest forms, are fully discussed along with their advantages and obstacles. Finally, the potential of microalgae biomass in biotechnological applications, biofuel production, as well as various biomass harvesting methods are described.

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Harvesting microalgae for health beneficial dietary supplements

Cited by 35 publications

References 102 publications

Microalgae as sources of green bioactives for health-enhancing food supplements and nutraceuticals: A review of literature

Microalgae as sources of green bioactives for health-enhancing food supplements and nutraceuticals: A review of literature

Membrane-Based Harvesting Processes for Microalgae and Their Valuable-Related Molecules: A Review

Recent advances in the bio-application of microalgae-derived biochemical metabolites and development trends of photobioreactor-based culture systems

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