Has asymptomatic inflammation of the prostate a role in outcome of patients with BPH treated by TURP?

Bucuras, V.; Botoca, M.; Cumpanas, A.; Dema, Alis; Muresan, Adriana; Miclea, F; Drăgan, P

doi:10.1016/s1569-9056(03)80070-2

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“…The significance of finding asymptomatic histopathological prostatic inflammation in the biopsy specimens of patients undergoing TURP has been debated. While some authors reported an association with outcomes [ 6 ], other researchers failed to demonstrate a definite association between this pathological entity and clinical outcomes after TURP [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

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Does asymptomatic prostatic inflammation alter the outcome of transurethral resection of prostate?

Dangi

Nagarajan

Panda

et al. 2017

CEJU

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IntroductionThere is contradictory evidence in literature with respect to the association of asymptomatic prostatic inflammation on biopsy with complications of Transurethral Resection of Prostate. The aim of the present study was to evaluate the association of prostatitis in biopsy specimens of patients undergoing transurethral resection of prostate with bladder neck contracture (the primary end point) and other complications.Material and methodsPatients who had undergone transurethral resection at a single centre between 2005 and 2010, with a minimum of 3 months follow-up were included. The study population was divided into two cohorts: those with inflammation on prostatic biopsy (Group A) and those without (Group B). These two groups were compared with respect to demographic data and pre-operative and intraoperative confounding factors. Immediate complications were documented using the modified Clavien-Dindo system and compared. Long term complications like bladder neck contracture, meatal stenosis, urethral stricture, and recurrent adenoma were also compared.ResultsBoth groups were comparable except for Group A patients having a higher median resected weight (20 vs. 14 gms, p = 0.009). There was no significant difference between the groups with respect to the rate of bladder neck contracture and other long-term and short term complications on univariate and multivariate analysis. Larger resected weight of gland was associated with lower rate of bladder neck contracture on multivariate analysis (p = 0.019, Odds ratio: 0.937).ConclusionsPresence of histologically confirmed prostatic inflammation is not associated with bladder neck contracture or other complications following transurethral resection. Smaller resected prostatic weight was associated with higher incidence of bladder neck contracture.

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Section: Discussionmentioning

confidence: 99%

“…Bucuras et. al did not find any association of histological prostatitis with intra-operative and post-operative complications following TURP [ 5 ], whereas Doluoglu et al, found that prostatic inflammation was associated with a higher number of re-interventions for urethral stricture and bladder neck contracture after TURP [ 6 ].…”

Section: Introductionmentioning

confidence: 99%