It was over 25 years ago that European Urban and Regional Studies was launched at a time of epochal change in the composition of the political, economic and social map of Europe. Brexit has been described as an epochal moment – and at such a moment, European Urban and Regional Studies felt it should offer the space for short commentaries on Brexit and its impact on the relationships of place, space and scale across the cultural, economic, social and political maps of the ‘new Europes’. Seeking contributions drawing on the theories, processes and patterns of urban and regional development, the following provides 10 contributions on Europe, the UK and/or their relational geographies in a post-Brexit world. What the drawn-out and highly contested process of Brexit has done for the populace, residents and ex-pats of the UK is to reveal the inordinate ways in which our mental, everyday and legal maps of the regions, nations and places of the UK in Europe are powerful, territorially and rationally inconsistent, downright quirky at times but also intensely unequal. First, as the UK exits the Single Market, the nature of the political imagination needed to create alternatives to the construction of new borders and new divisions, even within a discourse of creating a ‘global Britain’, remains uncertain. European Urban and Regional Studies has always been a journal dedicated to the importance of pan-European scholarly integration and solidarity and we hope that it will continue to intervene in debates over what alternative imaginings to a more closed and introverted future might look like. Second, as the impacts of COVID-19 continue to change in profound ways how we think, work and travel across European space, we will need to find new forms of integration and new forms of engagament in intellectual life and policy development. European Urban and Regional Studies remains commited to forging such forms.