Hashimoto tiroiditinin trombositler üzerine sayı, büyüklük ve dağılım açısından etkisi

Abstract

Objective: The aim of our study was to investigate whether platelet indices were affected in patients with Hashimoto's thyroiditis (HT). Method: 11 patients (10 female, 1 male) with HT and 26 subjects with nodular goiters (19 female, 7 male) selected as control group were included in the study. All cases were examined for complete blood count parameters (leukocyte count, neutrophil count and percentage, lymphocyte count and percentage, platelet count, plateletcrit, platelet distribution width (PDW), and mean platelet volume (MPV)). Results: Leukocyte count, neutrophil count and percentage, lymphocyte percentage, platelet count, plateletcrit, and MPV in the patient group were not statistically different from the control group. Lymphocyte count and PDW were significantly higher in patients with HT than in the control group. Conclusion: Our results suggest that patients with HT have higher PDW levels. Increased PDW in HT may be helpful in diagnosis, floow-up, and prognosis of the disease.

Relationship of the platelet distribution width/platelet count ratio with thyroid antibody levels in patients with Hashimoto's thyroiditis

“…In a study conducted by Güvendi et al. , 23 PDW was elevated in patients with Hashimoto’s thyroiditis. They suggested this indicated can be used for diagnosis and follow-up of the disease.…”

“…Bilge et al 22 found that MPV and PDW were high in patients with Hashimoto's thyroiditis and noted that these changes may be associated with inflammation and malignancy. In a study conducted by Gu¨vendi et al, 23 PDW was elevated in patients with Hashimoto's thyroiditis. They suggested this indicated can be used for diagnosis and follow-up of the disease.…”

“…They suggested this indicated can be used for diagnosis and follow-up of the disease. 23 Findikli and Tutak 24 observed increases in PDW and MPV in 60 female patients with subclinical hyperthyroidism. Li et al 25 investigated the diagnostic value of PDW and albumin levels in patients with thyroid nodules and malignancies.…”

“…They suggested this indicated can be used for diagnosis and follow-up of the disease. 23 Findikli and Tutak 24 observed increases in PDW and MPV in 60 female patients with subclinical hyperthyroidism. Li et al.…”

“…They suggested this indicated can be used for diagnosis and follow-up of the disease. 23 platelet/lymphocyte ratio (PLR) in 121 patients with hypothyroidism or subclinical hypothyroidism and determined that PLR may be useful in the course of inflammatory diseases. 26 Wen et al reported the prognostic value of MPV and PDW in a study of 558 patients with papillary thyroid cancer.…”