HAV Immunity in Iranian Medical Students

Hosseini-Shokouh, Seyyed-Javad; Dadashi, Alireza; Abiri, Mohamad; zohrevand, Iraj; Eshraghian, Ahad; Khoshdel, Alireza; Heidari, Behnam; Khoshkish, Shayan

doi:10.5812/hepatmon.26219

Cited by 10 publications

(8 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In similar studies in Turkey, anti-HAV seropositivity was reported as 51% [10], 27.3% [11] and 15% [12]. In Korea, anti-HAV seropositivity was reported as 11.4% among 1st-to 3rd-year medical school students [13], and in medical students in Iran, the prevalence of anti-HAV seropositivity was 70% in one study [14] and 34% in another study [15]. In another study from Italy, 3.16% of nursing students were immune to the HAV [16].…”

Section: Sexmentioning

confidence: 89%

Hepatitis A, B and C seropositivity among first-year healthcare students in western Turkey: a seroprevalence study

et al. 2020

View full text Add to dashboard Cite

Background: The risk of viral hepatitis among healthcare students (HCSs) is greater than that among the general population. Therefore, this study was conducted to investigate the seroprevalence of the hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV) among first-year HCSs at a university in Turkey and as a secondary objective, to determine the factors associated with HAV and HBV seropositivity. Methods: This cross-sectional study was performed in first-year HCSs in Izmir, western Turkey. Data were collected using a self-administered questionnaire including items on sociodemographic characteristics, medical history, and hygiene. A total of 650 HCSs were tested for the HAV, HBV and HCV markers. Categorical variables were compared using the chi-square test. The association between independent variables and anti-HAV seropositivity and anti-HBs seropositivity was assessed by multinomial logistic regression analysis. Results: The overall frequency of total anti-HAV seropositivity was 34.9%. HBsAg, total anti-HBc and anti-HBs seropositivity were found in 0.3, 1.2 and 93.7% of samples, respectively. All of the HCSs were negative for anti-HCV. Total anti-HAV seropositivity was found to be 1.73 times higher in those ≥21 years old, and it was 1.61 times higher in those who perceived their economic status to be average and 2.75 times higher in those who perceived their economic status to be low. Total anti-HAV seropositivity was found to be 4.37 times higher in those who lived in provinces with intermediate human development index levels. Total anti-HBs seropositivity was found to be 2.48 times higher in those ≤20 years old, and it was 2.13 times higher in those who perceived their economic status to be average. Conclusions: Approximately two out of three HCSs were susceptible to HAV infection. Since HCSs are at high risk for HAV infection, they should be vaccinated before medical clerkships begin. Our results indicate that there is a high prevalence of anti-HBs seropositivity among HCSs. This result may be largely attributed to the implementation of a successful vaccination program in Turkey since 1998.

show abstract

Section: Sexmentioning

confidence: 89%

Hepatitis A, B and C seropositivity among first-year healthcare students in western Turkey: a seroprevalence study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Another study in a district of Mazandaran found that educational levels, water supply, and sewage disposal systems did not affect HAV epidemiology (20). Conversely, in a sample of medical students in Tehran, clean water availability and higher levels of parents’ education were protective factors against the risk of HAV seropositivity (21), and in Fars province, higher household size was related to higher HAV prevalence (9). Sample size and sampling method might have influenced the results; however, it seems that basic infrastructures such as safe drinking water supply and sewage disposal, as well as primary health care education, which are the main determinants of HAV acquisition are to a large extent provided in most regions of the country (12).…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Prevalence and Risk Factors of Hepatitis A in 10 to 18-Year-Old Adolescents of Sixteen Iranian Provinces: The CASPIAN-III Study

et al. 2016

View full text Add to dashboard Cite

BackgroundHepatitis A is a common health concern both in developing and developed countries. Hygienic and socioeconomic parameters deeply impact the prevalence and transmission of this disease. Evaluating the epidemiological distribution and risk factors for Hepatitis A virus (HAV) is necessary for policy makers to improve local and national preventive measures.ObjectivesThe aim of this study was to compare the prevalence of hepatitis A infection in a sample of Iranian adolescents living in different provinces of Iran and to assess its family- and community-related risk factors.MethodsIn this cross-sectional study, serum samples of 10 to 18-year-old adolescents, who were studied in a national health survey, were examined for anti-HAV antibodies. A total of 2,494 subjects were included from 16 provinces by multistage random cluster sampling. Demographic and socioeconomic factors related to HAV transmission were extracted by valid questionnaires. A multilevel analysis using mixed-effects logistic regression (melogit) was used to evaluate the association of risk factors with HAV infection.ResultsThe weighted prevalence of HAV varied significantly across the studied provinces (P = 0.001), ranging from 50.43% in the Fars province to 78.81% in Markazi province. HAV was significantly more prevalent in children whose mothers worked outside of the home (OR, 1.73; 95% CI, 1.14-2.62; P = 0.009).ConclusionsThe risk of symptomatic HAV infection is considerable in adolescents of all studied provinces; thus, universal HAV vaccination is recommended for all adolescents, regardless of their socioeconomic level. However, the risk is higher in some provinces, which seem to be transitioning from intermediate to low endemicity.

show abstract

“…Medical students are another group investigated for HAV seroprevalence in Iran. A study in one of the medical universities of Tehran province in 2015 revealed that just 34% of evaluated patients (n = 270) had positive results for anti-HAV anti-body test ( 30 ). Another study in medical university of Babol in 2014 showed that more than 30% of medical students were not immune against HAV infection ( 31 ).…”

Section: Resultsmentioning

confidence: 99%

Hepatitis A Virus Infection, Vaccination and Iranian Healthcare Workers

et al. 2015

View full text Add to dashboard Cite

Context:Hepatitis A virus (HAV) infection is an important public health problem. It is estimated that about 1.4 million cases of HAV infection occur every year worldwide. Non-immune healthcare workers (HCWs) can be at higher risk of HAV infection in comparison to general population and an appropriate preventive method should be considered for them.Evidence Acquisition:For finding related articles, a comprehensive search was performed in Scopus, PubMed and Google Scholar and all appropriate combinations of following keywords were considered; “healthcare provider”, “healthcare personnel”, “healthcare worker”, “nurse” “medical students”, “Iran”, “Hepatitis A” and “vaccination”. Also we did a search in Persian language in Google scholar and scientific information database (SID) to find related Persian literature.Results:A gradual shift in age of HAV infection has been seen from childhood toward adulthood. Data about HAV seropositivity among Iranian HCWs are very limited. However based on the recent studies, it seems that HAV seropositivity has been reduced among HCWs in comparison with the past. All recent studies have suggested HAV vaccination for HCWs.Conclusions:Available limited studies show that Iranian healthcare personnel need HAV vaccination. However, for selecting an appropriate preventive method for this high risk group, more original studies are still needed.

show abstract

HAV Immunity in Iranian Medical Students

Cited by 10 publications

References 28 publications

Hepatitis A, B and C seropositivity among first-year healthcare students in western Turkey: a seroprevalence study

Hepatitis A, B and C seropositivity among first-year healthcare students in western Turkey: a seroprevalence study

Comparison of the Prevalence and Risk Factors of Hepatitis A in 10 to 18-Year-Old Adolescents of Sixteen Iranian Provinces: The CASPIAN-III Study

Hepatitis A Virus Infection, Vaccination and Iranian Healthcare Workers

Contact Info

Product

Resources

About