Hazardous alcohol use among patients with schizophrenia and depression

Subramaniam, Mythily; Mahesh, Mithila; Peh, Chao Xu; Tan, Junda; Fauziana, Restria; Satghare, Pratika; Gupta, Bhanu; Kandasami, Gomathinayagam; Chong, Siow Ann

doi:10.1016/j.alcohol.2017.07.008

Cited by 28 publications

(26 citation statements)

References 50 publications

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“…Additionally, individuals with a history of smoking were found to be more likely to report hazardous alcohol use. This finding is consistent with previous research indicating the frequent co-occurrence of smoking and excess alcohol use [23, 33, 34]. One study suggests that people who consider themselves to be risk takers were more likely to share a genetic risk with schizophrenia and be smokers [35].…”

Section: Discussionsupporting

confidence: 92%

“…The prevalence of hazardous alcohol use amongst patients with FEP reported in the current study can be compared to a similar study which examined hazardous alcohol use amongst psychiatric outpatients in Singapore (albeit with a sample population with a diagnosis of schizophrenia or depression) [23]. The prevalence of hazardous alcohol use in the current study among outpatients with FEP was found to be almost double (12.9%) compared to patients with schizophrenia (6.4%).…”

Section: Discussionmentioning

confidence: 57%

“…As such, one might hypothesise the hazardous alcohol use in a population of FEP patients in Singapore to be lower than those reported in Western countries. While there have been previous studies conducted that have examined AUDs amongst the general population in Singapore [21], AUDs amongst inpatients of a general hospital in Singapore [22] and hazardous alcohol use amongst psychiatric outpatients [23] in Singapore, this is the first study to date to examine hazardous alcohol use among patients with FEP in Singapore.…”

Section: Introductionmentioning

confidence: 99%

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Hazardous alcohol use in a sample of first episode psychosis patients in Singapore

et al. 2019

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BackgroundHazardous alcohol use has often been found to be more prevalent amongst psychiatric outpatients than the general population. Additionally, it has also been associated with poorer outcomes. The study aimed to investigate (1) the prevalence and (2) socio-demographic and clinical correlates of hazardous alcohol use, as well as (3) the relationship between hazardous alcohol use and quality of life in an outpatient sample with First Episode Psychosis (FEP) in Singapore.MethodsBaseline data (N = 280) was extracted from a longitudinal study investigating smoking and alcohol use amongst outpatients with FEP in a psychiatric hospital. Information on socio-demographics, hazardous alcohol use, and quality of life was collected through a self-report survey. Hazardous alcohol use was ascertained by total scores of 8 or higher on the Alcohol Use Disorders Identification Test (AUDIT). Data was analysed using logistic regression and linear regression analyses.ResultsThe prevalence of hazardous alcohol use over the past 12-month period was 12.9%. Those who had never smoked in their lifetime (vs current smokers) and those with a diagnosis of brief psychotic disorder (vs schizophrenia spectrum disorders) were found to have significantly lower odds of hazardous alcohol use. Hazardous alcohol use was also associated with lower negative symptom scores. Lastly, hazardous alcohol use was found to significantly predict lower scores on the physical health, social relationship and environment domains of quality of life.ConclusionsThe association between hazardous alcohol use and lower negative symptom scores is a surprising finding that needs to be further explored. The significant impact of hazardous alcohol use in reductions in quality of life suggests that early screening and interventions could benefit patients with hazardous alcohol use and comorbid psychosis.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 57%

Section: Introductionmentioning

confidence: 99%

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Hazardous alcohol use in a sample of first episode psychosis patients in Singapore

et al. 2019

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“…Educational status was strongly associated with alcohol abuse where those with lower education were more likely to be Epidemiology and Psychiatric Sciences 5 associated with alcohol abuse. This association has been found in previous studies in the local population (Subramaniam et al, 2012c;2017b) as well as in other countries (Andrade et al, 2002;Park et al, 2008). It has been suggested that better-educated people are less likely to engage in risky behaviors, such as smoking and drinking, and are more likely to have healthy behaviors related to diet and exercise.…”

Section: Discussionsupporting

confidence: 79%

Tracking the mental health of a nation: prevalence and correlates of mental disorders in the second Singapore mental health study

Subramaniam

Abdin

Vaingankar

et al. 2019

Epidemiol Psychiatr Sci

161

127

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Aims The second Singapore Mental Health Study (SMHS) – a nationwide, cross-sectional, epidemiological survey - was initiated in 2016 with the intent of tracking the state of mental health of the general population in Singapore. The study employed the same methodology as the first survey initiated in 2010. The SMHS 2016 aimed to (i) establish the 12-month and lifetime prevalence and correlates of major depressive disorder (MDD), dysthymia, bipolar disorder, generalised anxiety disorder (GAD), obsessive compulsive disorder (OCD) and alcohol use disorder (AUD) (which included alcohol abuse and dependence) and (ii) compare the prevalence of these disorders with reference to data from the SMHS 2010. Methods Door-to-door household surveys were conducted with adult Singapore residents aged 18 years and above from 2016 to 2018 (n = 6126) which yielded a response rate of 69.0%. The subjects were randomly selected using a disproportionate stratified sampling method and assessed using World Health Organization Composite International Diagnostic Interview version 3.0 (WHO-CIDI 3.0). The diagnoses of lifetime and 12-month selected mental disorders including MDD, dysthymia, bipolar disorder, GAD, OCD, and AUD (alcohol abuse and alcohol dependence), were based on the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria. Results The lifetime prevalence of at least one mood, anxiety or alcohol use disorder was 13.9% in the adult population. MDD had the highest lifetime prevalence (6.3%) followed by alcohol abuse (4.1%). The 12-month prevalence of any DSM-IV mental disorders was 6.5%. OCD had the highest 12-month prevalence (2.9%) followed by MDD (2.3%). Lifetime and 12-month prevalence of mental disorders assessed in SMHS 2016 (13.8% and 6.4%) was significantly higher than that in SMHS 2010 (12.0% and 4.4%). A significant increase was observed in the prevalence of lifetime GAD (0.9% to 1.6%) and alcohol abuse (3.1% to 4.1%). The 12-month prevalence of GAD (0.8% vs. 0.4%) and OCD (2.9% vs. 1.1%) was significantly higher in SMHS 2016 as compared to SMHS 2010. Conclusions The high prevalence of OCD and the increase across the two surveys needs to be tackled at a population level both in terms of creating awareness of the disorder and the need for early treatment. Youth emerge as a vulnerable group who are more likely to be associated with mental disorders and thus targeted interventions in this group with a focus on youth friendly and accessible care centres may lead to earlier detection and treatment of mental disorders.

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“… 5 The prevalence of alcohol use disorder (AUD) is higher among those with severe mental disorders as compared with the general population. 6–8 Different studies conducted in developing countries report that the co-morbidity rate of AUD in affective disorders and schizophrenia ranged from 11.3% to 56% 5 , 6 , 9 , 10 and 9.7% to 74% 5 , 6 , 11 respectively. The large variation in outcomes of such prevalence studies was attributed by the differences in study settings, study design, and AUD screening tool.…”

Section: Introductionmentioning

confidence: 99%

Alcohol Use Disorder and Its Associate Factors Relating to Patients with Severe Mental Disorders Attending Psychiatric Follow-Ups in Northwest Ethiopia

Kassew

Kiflie

Minichil

et al. 2021

NDT

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Background Patients with mental disorders have high rates of co-existing alcohol use disorder and vice versa. Alcohol use disorder has emerged as a major challenge to intervene patients with severe mental disorders. It is under-recognized and has not been investigated well in low-income countries like Ethiopia. The aim of this study was to assess the prevalence and associate factors of alcohol use disorder among patients with severe mental disorders attending psychiatric follow-ups at the University of Gondar comprehensive specialized hospital, northwest Ethiopia. Methods A total of 384 patients with severe mental disorders selected by a systematic random sampling technique took part in the interviews for this cross-sectional study. The alcohol use disorder identification test was used to assess the problem. Univariate and multivariate binary logistic regressions were computed to examine the associated factors. An adjusted odds ratio with a 95% confidence interval (CI) was used for reporting the result. Results The prevalence of alcohol use disorder among patients with severe mental disorders was 36.2%. Of the participants, 23.5%, 8.6%, and 4.1% had hazardous, harmful alcohol drinking and alcohol dependency, respectively. In the multivariate analysis, male sex, younger age, psychotic and bipolar disorder diagnoses, having poor social support, moderate and high perceived stress, and current tobacco smoking were factors significantly associated with alcohol use disorder. Conclusion The prevalence of alcohol use disorder among patients with severe mental disorders was found to be high. Early intervention and integrating treatment services for co-existing mental disorders and alcohol use disorder is important. The special treatment, where it is offered for young male patients and those with the diagnosis of psychotic and bipolar disorders, is recommended to promote the uptake of alcohol and mental health treatment services.

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Hazardous alcohol use among patients with schizophrenia and depression

Cited by 28 publications

References 50 publications

Hazardous alcohol use in a sample of first episode psychosis patients in Singapore

Hazardous alcohol use in a sample of first episode psychosis patients in Singapore

Tracking the mental health of a nation: prevalence and correlates of mental disorders in the second Singapore mental health study

Alcohol Use Disorder and Its Associate Factors Relating to Patients with Severe Mental Disorders Attending Psychiatric Follow-Ups in Northwest Ethiopia

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