Hazardous Events Associated With Impaired Olfactory Function

Santos, Daniel Valente de Oliveira; Reiter, Evan R.; DiNardo, Laurence J.; Costanzo, Richard M.

doi:10.1001/archotol.130.3.317

Cited by 270 publications

(214 citation statements)

References 16 publications

Supporting

Mentioning

188

Contrasting

Unclassified

Order By: Relevance

“…In a recent study of Drummond et al (41) that investigated patients after traumatic brain injury and resulting changes in their ability to smell, olfactory dysfunction was associated with significant impact on a range of activities and social roles, like work, relationship, personal hygiene and leisure. Santos et al demonstrated, that individuals with an olfactory disorder have at least twice the risk of being involved in potentially life-threatening situations (42). The latter includes detection of natural gas leakages or smoke and consuming of spoiled foods.…”

Section: Discussionmentioning

confidence: 99%

Functional Outcomes of Face Transplantation

Fischer

Kueckelhaus

Pauzenberger

et al. 2015

American Journal of Transplantation

View full text Add to dashboard Cite

In this study we provide a compilation of functional impairments before and improvements after face transplantation (FT) of five FT recipients of our institution and all FTs reported in current literature. Functional outcome included the ability to smell, breath, eat, speak, grimace and facial sensation. Before FT, all our patients revealed compromised ability to breath, eat, speak, grimace and experience facial sensation. The ability to smell was compromised in two of our five patients. Two patients were dependent on tracheostomy and one on gastrostomy tubes. After FT, all abilities were significantly improved and all patients were independent from artificial air airways and feeding tubes. Including data given in current literature about the other 24 FT recipients in the world, the abilities to smell, eat and feel were enhanced in 100% of cases, while the abilities of breathing, speaking and facial expressions were ameliorated in 93%, 71% and 76% of cases, respectively. All patients that required gastrostomy and 91% of patients depending on tracheostomy were decannulated after FT. Unfortunately, outcomes remain unreported in all other cases and therefore we are unable to comment on improvements.

show abstract

Section: Discussionmentioning

confidence: 99%

Functional Outcomes of Face Transplantation

Fischer

Kueckelhaus

Pauzenberger

et al. 2015

American Journal of Transplantation

View full text Add to dashboard Cite

show abstract

“…Also, smelling can modulate appetite, dietary behaviors, and nutritional status (Duffy et al, 1995;Aschenbrenner et al, 2008;Seo & Hummel, 2009). Moreover, olfaction warns of possible microbial threat (e.g., from feces, vomit, or organic decay), evoking disgust , and of nonmicrobial hazards including gas leaks, smoke, and toxic materials, eliciting fear (Cain & Turk, 1985;Cain et al, 1987;Miwa et al, 2001;Santos et al, 2004). We therefore tested the ability of the last-mentioned subjects to detect, describe and judge the smell of dimethyl-disulfide (DMDS) ), a byproduct of the decomposition of various foods which has a characteristic smell of rotten cabbage and is largely responsible for the smell of different decaying or putrefying foods including milk (van Aardt et al, 2005).…”

Section: Are These Findings Relevant For Everyday Life?mentioning

confidence: 99%

Adverse Effect of Air Pollution on Odor Perception

Guarneros¹,

Drucker-Colı́n²,

Esquivelzeta³

et al. 2011

Advanced Topics in Environmental Health and Air Pollution Case Studies

View full text Add to dashboard Cite

“…However, olfaction is a critical physiologic function in humans: normal perception is fundamental for detection of many warning signals of life-threatening situations, such as smoke, spoiled food, dangerous chemicals, gas leaks, etc. : in some studies a relation was observed between the degree of olfactory loss and the risk of hazardous events [1,2]. Furthermore, nutritional status and many other topics related to the quality of life may be affected by the impairment of olfactory function [3], and loss of smell is accompanied by an increased risk of depression [4].…”

Section: Introductionmentioning

confidence: 99%

Anosmia after exposure to a pyrethrin-based insecticide: A case report

Gobba

Abbacchini

2012

International Journal of Occupational Medicine and Environmental Health

View full text Add to dashboard Cite

We present the case of a subject developing anosmia, preceded by nasal transient irritation and short lasting phantosmia and torqosmia, upon re-entrance into a room treated with a pyrethrin-based insecticide. The concentration of the insecticide in the room is unknown, but relatively high levels are predicted basing upon the modality of exposure and by the irritation symptoms in the subject. Despite corticosteroids therapy, anosmia has persisted unmodified for more than three years; according to, and based on evidence in the literature on olfactory disturbance prognosis, anosmia in this patient is likely to be permanent. The significance of this case report is related to the current wide use of insecticides containing pyrethrin and pyrethroids and highlights the need for more adequate attention to lowering airborne concentrations of pyrethrins and pyrethroids prior to re-entering the treated rooms. In particular, in a closed space sprayed with pyrethrins and pyrethroids insecticide, any irritant symptoms and/or dysosmia should be immediately considered relevant warning signs, and must be avoided.

show abstract

Hazardous Events Associated With Impaired Olfactory Function

Abstract: To evaluate the risk of olfactory-related hazardous events in patients with impaired olfactory function.

Cited by 270 publications

References 16 publications

Functional Outcomes of Face Transplantation

Functional Outcomes of Face Transplantation

Adverse Effect of Air Pollution on Odor Perception

Anosmia after exposure to a pyrethrin-based insecticide: A case report

Contact Info

Product

Resources

About